RT Journal Article
T1 Use of Intra-aortic Balloon Pump as a Bridge to Heart Transplant in Spain: Results From the ASIS-TC Study.
A1 Barge-Caballero, Eduardo
A1 González-Vílchez, Francisco
A1 Delgado, Juan F
A1 Mirabet-Pérez, Sonia
A1 González-Costello, José
A1 Pérez-Villa, Félix
A1 Martínez-Sellés, Manuel
A1 Segovia-Cubero, Javier
A1 Hervás-Sotomayor, Daniela
A1 Blasco-Peiró, Teresa
A1 De la Fuente-Galán, Luis
A1 Lambert-Rodríguez, José Luis
A1 Rangel-Sousa, Diego
A1 Almenar-Bonet, Luis
A1 Garrido-Bravo, Iris P
A1 Rábago-Juan-Aracil, Gregorio
A1 Muñiz, Javier
A1 Crespo-Leiro, María G
K1 Asistencia circulatoria mecánica
K1 Balón de contrapulsación intraaórtico
K1 Heart transplant
K1 Intra-aortic balloon pump
K1 Mechanical circulatory support
K1 Trasplante cardiaco
AB In Spain, intra-aortic balloon pump (IABP) has been used frequently as a bridge to urgent heart transplant (HT). We sought to analyze the clinical outcomes of this strategy. We conducted a case-by-case, retrospective review of clinical records of 281 adult patients listed for urgent HT under IABP support in 16 Spanish institutions from 2010 to 2015. Pre- and post-transplant survival and adverse clinical events were analyzed. A total of 194 (69%, 95%CI, 63.3-74.4) patients were transplanted and 20 (7.1%, 95%CI, 4.4-10.8) died during a mean period of IABP support of 10.9±9.7 days. IABP support was withdrawn before an organ became available in 32 (11.4%) patients. Thirty-five (12.5%, 95%CI, 8.8-16.9) patients transitioned from IABP to full-support mechanical devices. Mean urgent waiting list time increased from 5.9±6.3 days in 2010 to 15±11.7 days in 2015 (P=.001). Post-transplant survival rates at 30-days, 1-year, and 5-years were 88.1% (95%CI, 85.7-90.5), 76% (95%CI, 72.9-79.1), and 67.8% (95%CI, 63.7-71.9), respectively. The incidence rate of major adverse clinical outcomes-device dysfunction, stroke, bleeding or infection-during IABP support was 26 (95%CI, 20.6-32.4) episodes per 1000 patient-days. The incidence rate of IABP explantation due to complications was 7.2 (95%CI, 4.5-10.8) cases per 1000 patient-days. In a setting of short waiting list times, IABP can be used to bridge candidates to urgent HT with acceptable postoperative results, but there were significant rates of adverse clinical events during support.
YR 2018
FD 2018-08-13
LK https://hdl.handle.net/10668/25938
UL https://hdl.handle.net/10668/25938
LA en
LA es
DS RISalud
RD Apr 17, 2025