TY - JOUR AU - Hernández-Camarero, Pablo AU - López-Ruiz, Elena AU - Marchal, Juan Antonio AU - Perán, Macarena PY - 2021 DO - 10.1186/s13046-021-02022-5 UR - http://hdl.handle.net/10668/4407 T2 - Journal of Experimental and Clinical Cancer Research AB - It has been well documented that the tumor microenvironment (TME) plays a key role in the promotion of drug resistance, the support of tumor progression, invasiveness, metastasis, and even the maintenance of a cancer stem-like phenotype. Here, we... LA - en PB - BioMed Central, Springer Nature KW - Tumor microenvironment KW - Metastasis KW - Pre-metastatic niche KW - Cancer-associated fibroblasts KW - Tumor-associated macrophages KW - Myofibroblasts KW - Stromal cells KW - Microambiente tumoral KW - Fibroblastos asociados al cáncer KW - Macrófagos asociados a tumores KW - Miofibroblastos KW - Células del estroma KW - Metástasis de la neoplasia KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment KW - Medical Subject Headings::Information Science::Information Science::Communication::Cybernetics::Feedback KW - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts::Myofibroblasts KW - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Stromal Cells KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype KW - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Neoplasm Metastasis TI - Cancer: a mirrored room between tumor bulk and tumor microenvironment TY - review article ER -