RT Journal Article T1 EEN Yesterday and Today … CDED Today and Tomorrow. A1 Herrador-Lopez, Marta A1 Martin-Masot, Rafael A1 Navas-Lopez, Victor Manuel K1 CDED K1 Crohn’s disease K1 adults K1 children K1 dietary treatment K1 exclusive enteral nutrition K1 treatment AB The treatment of Pediatric Crohn's Disease (CD) requires attention both to achieve mucosal healing and to optimize growth, while also maintaining proper bone health. Exclusive Enteral Nutrition (EEN) is recommended as first-line treatment in luminal CD. The therapeutic mechanisms of EEN are being discovered by advances in the study of the gut microbiota. Although the total exclusion of a normal diet during the time of EEN continues to be of high importance, new modalities of dietary treatment suggest a successful future for the nutritional management of CD. In this sense, Crohn's Disease Exclusion Diet (CDED) is a long-term strategy, it apparently acts on the mechanisms that influence the appearance of inflammation (reducing dietary exposure to products negatively affecting the microbiota), but does so using specific available whole foods to achieve this goal, increases the time of clinical remission and promotes healthy lifestyle habits. The development of CDED, which partly minimizes the problems of EEN, has enabled a turnaround in the treatment of pediatric CD. This review highlights the role of enteral nutrition in the treatment of Crohn's disease with special emphasis on newer dietary modalities such as CDED. PB MDPI AG YR 2020 FD 2020-12-08 LK http://hdl.handle.net/10668/16797 UL http://hdl.handle.net/10668/16797 LA en NO Jemes-Campaña IC, Romero-Galisteo RP, Labajos-Manzanares MT, Gálvez-Ruiz P, Moreno-Morales N. The Inventory of Quality in Early Intervention Centres for Service Providers: Preliminary Validating Study in a Spanish Sample. Int J Environ Res Public Health. 2020 Apr 9;17(7):2581 NO To Jalil Benyacoub for his support and contribution in critically reviewing this manuscript. DS RISalud RD Apr 12, 2025