TY - JOUR AU - Barbado, M Victoria AU - Medrano, Mayte AU - Caballero-Velazquez, Teresa AU - Alvarez-Laderas, Isabel AU - Sanchez-Abarca, Luis Ignacio AU - Garcia-Guerrero, Estefania AU - Martin-Sanchez, Jesus AU - Rosado, Ivan Valle AU - Piruat, Jose Ignacio AU - Gonzalez-Naranjo, Pedro AU - Campillo, Nuria Eugenia AU - Paez, Juan Antonio AU - Perez-Simon, Jose Antonio PY - 2016 DO - 10.1002/ijc.30483 UR - http://hdl.handle.net/10668/10558 T2 - International journal of cancer AB - Although hematopoietic and immune system show high levels of the cannabinoid receptor CB2, the potential effect of cannabinoids on hematologic malignancies has been poorly determined. Here we have investigated their anti-tumor effect in multiple... LA - en PB - John Wiley & Sons, Inc. KW - apoptosis KW - cannabinoids KW - caspases KW - ceramides KW - multiple myeloma KW - Animals KW - Antineoplastic Agents KW - Apoptosis KW - Cannabinoids KW - Caspase 2 KW - Cell Line, Tumor KW - Ceramides KW - Humans KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Multiple Myeloma KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Proto-Oncogene Proteins c-akt KW - Receptor, Cannabinoid, CB2 KW - Signal Transduction KW - Sphingolipids KW - bcl-X Protein TI - Cannabinoid derivatives exert a potent anti-myeloma activity both in vitro and in vivo. TY - research article VL - 140 ER -