RT Journal Article T1 Influence of Maternal and Paternal History of Mental Health in Clinical, Social Cognition and Metacognitive Variables in People with First-Episode Psychosis. A1 Mendoza-Garcia, Sara A1 Garcia-Mieres, Helena A1 Lopez-Carrilero, Raquel A1 Sevilla-Lewellyn-Jones, Julia A1 Birules, Irene A1 Barajas, Ana A1 Lorente-Rovira, Ester A1 Gutierrez-Zotes, Alfonso A1 Grasa, Eva A1 Pousa, Esther A1 Pelaez, Trini A1 Barrigon, Maria Luisa A1 Gonzalez-Higueras, Fermin A1 Ruiz-Delgado, Isabel A1 Cid, Jordi A1 Montserrat, Roger A1 Martin-Iñigo, Laia A1 Moreno-Kustner, Berta A1 Vila-Bbadia, Regina A1 Diaz-Cutraro, Luciana A1 Verdaguer-Rodriguez, Marina A1 Ferrer-Quintero, Marta A1 Punsoda-Puche, Paola A1 Barrau-Sastre, Paula A1 Moritz, Steffen A1 Ochoa, Susana K1 Attribution K1 Delusion K1 Family loading K1 First degree relatives K1 Psychotic spectrum disorder AB This study investigates, for the first time, clinical, cognitive, social cognitive and metacognitive differences in people diagnosed with first-episode of psychosis (FEP) with and without a family history of mental disorder split by maternal and paternal antecedents. A total of 186 individuals with FEP between 18 and 45 years old were recruited in community mental-health services. A transversal, descriptive, observational design was chosen for this study. Results suggest that there is a higher prevalence of maternal history of psychosis rather than paternal, and furthermore, these individuals exhibit a specific clinical, social and metacognitive profile. Individuals with a maternal history of mental disorder scored higher in delusional experiences, inhibition of the response to a stimulus and higher emotional irresponsibility while presenting a poorer overall functioning as compared to individuals without maternal history. Individuals with paternal history of mental disorder score higher in externalizing attributional bias, irrational beliefs of need for external validation and high expectations. This study elucidates different profiles of persons with FEP and the influence of the maternal and paternal family history on clinical, cognitive, social and metacognitive variables, which should be taken into account when offering individualized early treatment. PB MDPI SN 2075-4426 YR 2022 FD 2022-10-18 LK http://hdl.handle.net/10668/21390 UL http://hdl.handle.net/10668/21390 LA en NO Mendoza-García S, García-Mieres H, Lopez-Carrilero R, Sevilla-Lewellyn-Jones J, Birulés I, Barajas A, et al. Influence of Maternal and Paternal History of Mental Health in Clinical, Social Cognition and Metacognitive Variables in People with First-Episode Psychosis. J Pers Med. 2022 Oct 18;12(10):1732 NO This work was supported by the Instituto de Salud Carlos III (Spanish Government) (PI11/01347, PI14/00044, PI18/00212), by the Fondo Europeo de Desarrollo Regional (FEDER), Progress and Health Foundation of the Andalusian Regional Ministry of Health (PI-0634/2011 and PI-0193/2014), Obra Social La Caixa (RecerCaixa call 2013), Generalitat de Catalunya, Health Depatment, PERIS call (SLT006/17/00231), Obra Social Sant Joan de Déu (BML) and CERCA Programme/Generalitat de Catalunya. DS RISalud RD Apr 8, 2025