RT Journal Article T1 Mediterranean-style breakfast increases postprandial serum alpha-tocopherol levels in lean and obese individuals A1 Garcia-Rodriguez, S. A1 Sinausia, L. A1 Barragan, C. A1 Montero, E. A1 Perona, J. S. K1 alpha-tocopherols Breakfast K1 Mediterranean-style meal K1 Obesity K1 Postprandial K1 Western-style meal K1 Vitamin-e K1 Gamma-tocopherol K1 Normal-weight K1 Plasma K1 Diet K1 Ldl K1 Supplementation K1 Carotenoids K1 Combination K1 Resistance AB The aim of this study was to compare the variations in the concentrations of tocopherols and retinol in obese adults in the postprandial state after the intake of a Mediterranean or Western-style breakfast. The study was designed as a randomized, controlled intervention trial in the postprandial state, for which 24 male adults (12 obese and 12 of normalweight) were recruited. After a fat challenge, blood samples were collected at different times postprandially and alpha-tocophcrol, gamma-tocopherol and retinal concentrations were determined in serum by HPLC. The Mediterranean-style meal produced a greater increase in serum a-tocopherol levels in both obese and normal-weight subjects, compared to the Western-style meal, indicating that the composition of the food allects the concentration of tocopherols in the postprandial state. However, the serum concentrations of gamma-tocopherol and retinol remained unmodified. In conclusion, the presence of alpha-tocopherol in the meal could contribute to the protection of the Mediterranean-style meal against atherosclerosis in the postprandial state. PB Consejo superior investigaciones cientificas-csic SN 0017-3495 YR 2018 FD 2018-07-01 LK http://hdl.handle.net/10668/19346 UL http://hdl.handle.net/10668/19346 LA en DS RISalud RD Apr 6, 2025