RT Journal Article
T1 Outlook on the neuroprotective effect of estrogen.
A1 d'Anglemont de Tassigny, Xavier
K1 Estrogens
K1 Estradiol
K1 Nervous system diseases
K1 Estriol
K1 Brain diseases
AB Epidemiologic studies often consider gender differences in a particular pathology, and constantly observe variations between men and women. Indeed, a remarkable sexual dimorphism exists in the epidemiology of neurological conditions and brain diseases. Physiologically, males and females differ by their levels of circulating hormones that drive sexual behavioral, as well as endocrine functions. Estrogen is the primary female sex hormonal group that enwraps estradiol, estrone and estriol, and which are the major naturally occurring hormones prevalent in women. Their role in the reproductive function has long been established, although the ubiquitous expression of its receptors (alpha, beta and G protein-coupled, GPR30) presumes a broader spectrum of action. This short review will summarize the current knowledge in estrogen therapy with particular focus on some of the recent work that might lead to new neuroprotective treatments.
PB Wolters Kluwer - Medknow Publications and Media Pvt. Ltd.
SN 1673-5374
YR 2017
FD 2017
LK https://hdl.handle.net/10668/27851
UL https://hdl.handle.net/10668/27851
LA en
NO d'Anglemont de Tassigny X. Outlook on the neuroprotective effect of estrogen. Neural Regen Res. 2017 Nov;12(11):1799-1800
DS RISalud
RD Apr 3, 2025