TY - JOUR AU - Gamez-Belmonte, Reyes AU - Tena-Garitaonaindia, Mireia AU - Hernandez-Chirlaque, Cristina AU - Cordova, Samir AU - Ceacero-Heras, Diego AU - de Medina, Fermin Sanchez AU - Martinez-Augustin, Olga PY - 2020 DO - 10.3390/ijms22010051 UR - http://hdl.handle.net/10668/16864 T2 - International journal of molecular sciences AB - The liver expresses tissue-nonspecific alkaline phosphatase (TNAP), which may participate in the defense against bacterial components, in cell regulation as part of the purinome or in bile secretion, among other roles. We aimed to study the role of... LA - en PB - MDPI KW - Biliary acids KW - Metabolic syndrome KW - Methionine and choline diet KW - Steatohepatitis KW - Tissue non-specific alkaline phosphatase KW - Alkaline Phosphatase KW - Alleles KW - Animals KW - Choline KW - Choline Deficiency KW - Diet KW - Diet, High-Fat KW - Disease Models, Animal KW - Enzyme Activation KW - Fatty Liver KW - Methionine KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinases KW - PPAR alpha KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction TI - Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet. TY - research article VL - 22 ER -