TY - JOUR AU - Navarrete, Carmen AU - Garcia-Martin, Adela AU - Correa-Saez, Alejandro AU - Prados, Maria E. AU - Fernandez, Francisco AU - Pineda, Rafael AU - Mazzone, Massimiliano AU - Alvarez-Benito, Marina AU - Calzado, Marco A AU - Muñoz, Eduardo PY - 2022 DO - 10.1186/s12974-022-02540-9 UR - http://hdl.handle.net/10668/20333 T2 - Journal of neuroinflammation AB - Traumatic brain injury (TBI) is characterized by a primary mechanical injury and a secondary injury associated with neuroinflammation, blood-brain barrier (BBB) disruption and neurodegeneration. We have developed a novel cannabidiol aminoquinone... LA - en PB - BioMed Central KW - Brain–blood barrier KW - Hypoxia-inducible factor KW - Neuroprotection KW - Prolyl-hydroxylases KW - Protein phosphatase 2A KW - Traumatic brain injury KW - Animals KW - Blood-Brain Barrier KW - Brain Injuries, Traumatic KW - Cannabidiol KW - Disease Models, Animal KW - Endothelial Cells KW - Mice KW - Neovascularization, Pathologic TI - A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injury. TY - research article VL - 19 ER -