RT Journal Article T1 Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries. A1 Deschasaux, Mélanie A1 Huybrechts, Inge A1 Julia, Chantal A1 Hercberg, Serge A1 Egnell, Manon A1 Srour, Bernard A1 Kesse-Guyot, Emmanuelle A1 Latino-Martel, Paule A1 Biessy, Carine A1 Casagrande, Corinne A1 Murphy, Neil A1 Jenab, Mazda A1 Ward, Heather A A1 Weiderpass, Elisabete A1 Overvad, Kim A1 Tjønneland, Anne A1 Rostgaard-Hansen, Agnetha Linn A1 Boutron-Ruault, Marie-Christine A1 Mancini, Francesca Romana A1 Mahamat-Saleh, Yahya A1 Kühn, Tilman A1 Katzke, Verena A1 Bergmann, Manuela M A1 Schulze, Matthias B A1 Trichopoulou, Antonia A1 Karakatsani, Anna A1 Peppa, Eleni A1 Masala, Giovanna A1 Agnoli, Claudia A1 De Magistris, Maria Santucci A1 Tumino, Rosario A1 Sacerdote, Carlotta A1 Boer, Jolanda Ma A1 Verschuren, Wm Monique A1 van der Schouw, Yvonne T A1 Skeie, Guri A1 Braaten, Tonje A1 Redondo, M Luisa A1 Agudo, Antonio A1 Petrova, Dafina A1 Colorado-Yohar, Sandra M A1 Barricarte, Aurelio A1 Amiano, Pilar A1 Sonestedt, Emily A1 Ericson, Ulrika A1 Otten, Julia A1 Sundström, Björn A1 Wareham, Nicholas J A1 Forouhi, Nita G A1 Vineis, Paolo A1 Tsilidis, Konstantinos K A1 Knuppel, Anika A1 Papier, Keren A1 Ferrari, Pietro A1 Riboli, Elio A1 Gunter, Marc J A1 Touvier, Mathilde AB To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers towards healthier food choices, is associated with mortality. Population based cohort study. European Prospective Investigation into Cancer and Nutrition (EPIC) cohort from 23 centres in 10 European countries. 521 324 adults; at recruitment, country specific and validated dietary questionnaires were used to assess their usual dietary intakes. A FSAm-NPS score was calculated for each food item per 100 g content of energy, sugars, saturated fatty acids, sodium, fibre, and protein, and of fruit, vegetables, legumes, and nuts. The FSAm-NPS dietary index was calculated for each participant as an energy weighted mean of the FSAm-NPS score of all foods consumed. The higher the score the lower the overall nutritional quality of the diet. Associations between the FSAm-NPS dietary index score and mortality, assessed using multivariable adjusted Cox proportional hazards regression models. After exclusions, 501 594 adults (median follow-up 17.2 years, 8 162 730 person years) were included in the analyses. Those with a higher FSAm-NPS dietary index score (highest versus lowest fifth) showed an increased risk of all cause mortality (n=53 112 events from non-external causes; hazard ratio 1.07, 95% confidence interval 1.03 to 1.10, P In this large multinational European cohort, consuming foods with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher mortality for all causes and for cancer and diseases of the circulatory, respiratory, and digestive systems, supporting the relevance of FSAm-NPS to characterise healthier food choices in the context of public health policies (eg, the Nutri-Score) for European populations. This is important considering ongoing discussions about the potential implementation of a unique nutrition labelling system at the European Union level. PB BMJ YR 2020 FD 2020-08-03 LK http://hdl.handle.net/10668/16264 UL http://hdl.handle.net/10668/16264 LA en NO Deschasaux M, Huybrechts I, Julia C, Hercberg S, Egnell M, Srour B, et al. Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries. BMJ. 2020 Sep 16;370:m3173 DS RISalud RD Apr 20, 2025