TY - JOUR AU - Santos-Nogueira, Eva AU - López-Serrano, Clara AU - Hernández, Joaquim AU - Lago, Natalia AU - Astudillo, Alma M AU - Balsinde, Jesús AU - Estivill-Torrús, Guillermo AU - Rodríguez de Fonseca, Fernando AU - Chun, Jerold AU - López-Vales, Rubèn PY - 2015 DO - 10.1523/JNEUROSCI.4703-14.2015 SN - 0270-6474 UR - http://hdl.handle.net/10668/2219 T2 - The Journal of Neuroscience : the official journal of the Society for Neuroscience AB - UNLABELLEDLysophosphatidic acid (LPA) is an extracellular lipid mediator involved in many physiological functions that signals through six known G-protein-coupled receptors (LPA1-LPA6). A wide range of LPA effects have been identified in the CNS,... LA - en PB - Society for Neuroscience KW - Demyelination KW - Lysophosphatidic acid KW - Microgria KW - Neuroprotection KW - Oligodendrocytes KW - Spinal cord injury KW - Potenciales evocados motores KW - Lisofosfolípidos KW - Ratas KW - ratones consanguíneos C57BL KW - Ratones transgénicos KW - Microglía KW - Actividad motora KW - Oligodendroglía KW - Receptores de ácidos lisofosfatídicos KW - Médula espinal KW - traumatismos de la médula espinal KW - Factores de tiempo KW - Animales recién nacidos KW - Células cultivadas KW - Muerte celular KW - Corteza cerebral KW - Enfermedades desmielinizantes KW - Modelos de enfermedad en animales KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Newborn KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex KW - Medical Subject Headings::Diseases::Nervous System Diseases::Demyelinating Diseases KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Animal::Disease Models, Animal KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Electrophysiological Phenomena::Evoked Potentials KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Chemicals and Drugs::Lipids::Membrane Lipids::Phospholipids KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice, Inbred Strains::Mice, Inbred C57BL KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Genetically Modified::Mice, Transgenic KW - Medical Subject Headings::Anatomy::Cells::Neuroglia::Microglia KW - Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity KW - Medical Subject Headings::Anatomy::Cells::Neuroglia::Oligodendroglia KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Lysophospholipid::Receptors, Lysophosphatidic Acid KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Spinal Cord KW - Medical Subject Headings::Diseases::Wounds and Injuries::Spinal Cord Injuries KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors KW - Medical Subject Headings::Organisms::Eukaryota::Animals TI - Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. TY - research article ER -