TY  - JOUR
AU  - Morell, María
AU  - Varela, Nieves
AU  - Castillejo-Lopez, Casimiro
AU  - Coppard, Celine
AU  - Luque, Maria Jose
AU  - Wu, Ying-Yu
AU  - Martin-Morales, Natividad
AU  - Perez-Cozar, Francisco
AU  - Gomez-Hernandez, Gonzalo
AU  - Kumar, Ramesh
AU  - O'Valle, Francisco
AU  - Alarcon-Riquelme, Marta E
AU  - Marañon, Concepcion
PY  - 2022
DO  - 10.1016/j.ebiom.2021.103808
UR  - http://hdl.handle.net/10668/22160
T2  - EBioMedicine
AB  - Type I IFN (IFN-I) is a family of cytokines involved in the pathogenesis of autoimmune and autoinflammatory diseases such as psoriasis. SIDT1 is an ER-resident protein expressed in the lymphoid lineage, and involved in anti-viral IFN-I responses in...
LA  - en
PB  - Science Direct
KW  - IFN-I
KW  - IRF7
KW  - Proinflammatory cytokines
KW  - Psoriasis
KW  - SIDT1
KW  - TLR7
KW  - TLR9
KW  - pDC
KW  - Animals
KW  - Dendritic Cells
KW  - Humans
KW  - Imiquimod
KW  - Mice
KW  - Nucleic Acids
KW  - Psoriasis
KW  - Toll-Like Receptor 7
KW  - Toll-Like Receptor 9
TI  - SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model.
TY  - research article
VL  - 76
ER  -