RT Journal Article T1 Effectiveness of Psychological and/or Educational Interventions in the Prevention of Anxiety: A Systematic Review, Meta-analysis, and Meta-regression. A1 Moreno-Peral, Patricia A1 Conejo-Cerón, Sonia A1 Rubio-Valera, Maria A1 Fernández, Anna A1 Navas-Campaña, Desirée A1 Rodríguez-Morejón, Alberto A1 Motrico, Emma A1 Rigabert, Alina A1 Luna, Juan de Dios A1 Martín-Pérez, Carlos A1 Rodríguez-Bayón, Antonina A1 Ballesta-Rodríguez, María Isabel A1 Luciano, Juan Vicente A1 Bellón, Juan Ángel AB To our knowledge, no systematic reviews or meta-analyses have been conducted to assess the effectiveness of preventive psychological and/or educational interventions for anxiety in varied populations. To evaluate the effectiveness of preventive psychological and/or educational interventions for anxiety in varied population types. A systematic review and meta-analysis was conducted based on literature searches of MEDLINE, PsycINFO, Web of Science, EMBASE, OpenGrey, Cochrane Central Register of Controlled Trials, and other sources from inception to March 7, 2017. A search was performed of randomized clinical trials assessing the effectiveness of preventive psychological and/or educational interventions for anxiety in varying populations free of anxiety at baseline as measured using validated instruments. There was no setting or language restriction. Eligibility criteria assessment was conducted by 2 of us. Data extraction and assessment of risk of bias (Cochrane Collaboration's tool) were performed by 2 of us. Pooled standardized mean differences (SMDs) were calculated using random-effect models. Heterogeneity was explored by random-effects meta-regression. Incidence of new cases of anxiety disorders or reduction of anxiety symptoms as measured by validated instruments. Of the 3273 abstracts reviewed, 131 were selected for full-text review, and 29 met the inclusion criteria, representing 10 430 patients from 11 countries on 4 continents. Meta-analysis calculations were based on 36 comparisons. The pooled SMD was -0.31 (95% CI, -0.40 to -0.21; P  Psychological and/or educational interventions had a small but statistically significant benefit for anxiety prevention in all populations evaluated. Although more studies with larger samples and active comparators are needed, these findings suggest that anxiety prevention programs should be further developed and implemented. YR 2017 FD 2017 LK http://hdl.handle.net/10668/11560 UL http://hdl.handle.net/10668/11560 LA en DS RISalud RD Mar 18, 2025