TY - JOUR AU - Ni, Guiyan AU - Zeng, Jian AU - Revez, Joana A AU - Wang, Ying AU - Zheng, Zhili AU - Ge, Tian AU - Restuadi, Restuadi AU - Kiewa, Jacqueline AU - Nyholt, Dale R AU - Coleman, Jonathan R I AU - Smoller, Jordan W AU - Schizophrenia Working Group of the Psychiatric Genomics Consortium AU - Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium AU - Yang, Jian AU - Visscher, Peter M AU - Wray, Naomi R PY - 2021 DO - 10.1016/j.biopsych.2021.04.018 UR - https://hdl.handle.net/10668/27781 T2 - Biological psychiatry AB - Polygenic scores (PGSs), which assess the genetic risk of individuals for a disease, are calculated as a weighted count of risk alleles identified in genome-wide association studies. PGS methods differ in which DNA variants are included and the... LA - en KW - LDpred2 KW - Lassosum KW - Major depressive disorder KW - MegaPRS KW - PRS-CS KW - Polygenic scores KW - Psychiatric disorders KW - Risk prediction KW - SBayesR KW - Schizophrenia KW - Depressive Disorder, Major KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - Humans KW - Mental Disorders KW - Multifactorial Inheritance KW - Schizophrenia TI - A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts. TY - research article VL - 90 ER -