RT Journal Article
T1 How to Handle Concomitant Asymptomatic Prosthetic Joints During an Episode of Hematogenous Periprosthetic Joint Infection, a Multicenter Analysis.
A1 Wouthuyzen-Bakker, Marjan
A1 Sebillotte, Marine
A1 Arvieux, Cedric
A1 Fernandez-Sampedro, Marta
A1 Senneville, Eric
A1 Barbero, Jose Maria
A1 Lora-Tamayo, Jaime
A1 Aboltins, Craig
A1 Trebse, Rihard
A1 Salles, Mauro Jose
A1 Kramer, Tobias Siegfried
A1 Ferrari, Matteo
A1 Garcia-Cañete, Joaquin
A1 Benito, Natividad
A1 Diaz-Brito, Vicens
A1 Del Toro, Maria Dolores
A1 Scarborough, Matthew
A1 Soriano, Alex
K1 asymptomatic
K1 bacteremia
K1 hematogenous
K1 late acute
K1 periprosthetic joint infection
AB Prosthetic joints are at risk of becoming infected during an episode of bacteremia, especially during Staphylocococcus aureus bacteremia. However, it is unclear how often asymptomatic periprosthetic joint infection (PJI) occurs, and whether additional diagnostics should be considered. In this multicenter study, we retrospectively analyzed a cohort of patients with a late acute (hematogenous) PJI between 2005-2015 who had concomitant prosthetic joints in situ. Patients without at least 1 year of follow-up were excluded. We included 91 patients with a hematogenous PJI and 108 concomitant prosthetic joints. The incident PJI was most frequently caused by Staphylococcus aureus (43%), followed by streptococci (26%) and Gram-negative rods (18%). Of 108 concomitant prosthetic joints, 13 were symptomatic, of which 10 were subsequently diagnosed as a second PJI. Of the 95 asymptomatic prosthetic joints, 1 PJI developed during the follow-up period and was classified as a "missed" PJI at the time of bacteremia with S. aureus (1.1%). Infected prosthetic joints were younger than the noninfected ones in 67% of cases, and prosthetic knees were affected more often than prosthetic hips (78%). During an episode of hematogenous PJI, concomitant asymptomatic prosthetic joints have a very low risk of being infected, and additional diagnostic work-up for these joints is not necessary.
YR 2021
FD 2021-08-12
LK https://hdl.handle.net/10668/27156
UL https://hdl.handle.net/10668/27156
LA en
NO Wouthuyzen-Bakker M, Sebillotte M, Arvieux C, Fernandez-Sampedro M, Senneville E, Barbero JM, et al.  How to Handle Concomitant Asymptomatic Prosthetic Joints During an Episode of Hematogenous Periprosthetic Joint Infection, a Multicenter Analysis. Clin Infect Dis. 2021 Dec 6;73(11):e3820-e3824.
DS RISalud
RD Apr 4, 2025