TY  - JOUR
AU  - Borroto-Escuela, Dasiel O.
AU  - Wydra, Karolina
AU  - Fores-Pons, Ramon
AU  - Vasudevan, Lakshmi
AU  - Romero-Fernandez, Wilber
AU  - Frankowska, Małgorzata
AU  - Ferraro, Luca
AU  - Beggiato, Sarah
AU  - Crespo-Ramirez, Minerva
AU  - Rivera, Alicia
AU  - Rocha, Luisa L.
AU  - Perez de la Mora, Miguel
AU  - Stove, Christophe
AU  - Filip, Małgorzata
AU  - Fuxe, Kjell
PY  - 2021
DO  - 10.3389/fphar.2021.627032
UR  - http://hdl.handle.net/10668/4551
T2  - Frontiers in Pharmacology
AB  - The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was proposed that they form the...
LA  - en
PB  - Frontiers
KW  - G protein-coupled receptor
KW  - Mu opioid receptor
KW  - Dopamine D2 receptor
KW  - Adenosine A2A receptor
KW  - Morphine use disorder
KW  - Cocaine use disorder
KW  - Oligomerization
KW  - Morphine
KW  - Neurons
KW  - Enkephalins
KW  - Receptores acoplados a proteínas G
KW  - Receptores opioides mu
KW  - Receptores de dopamina D2
KW  - Receptor de adenosina A2A
KW  - Morfina
KW  - Trastornos relacionados con sustancias
KW  - Cocaína
KW  - Neuronas
KW  - Encefalinas
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Subunits
KW  - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Polycyclic Hydrocarbons, Aromatic::Phenanthrenes::Morphinans::Morphine Derivatives::Morphine
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Central Nervous System Depressants::Narcotics::Analgesics, Opioid
KW  - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Learning::Reinforcement (Psychology)::Reward
KW  - Medical Subject Headings::Anatomy::Nervous System::Neurons
KW  - Medical Subject Headings::Diseases::Chemically-Induced Disorders::Substance-Related Disorders
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Aza Compounds::Azabicyclo Compounds::Tropanes::Cocaine
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Neuropeptides::Opioid Peptides::Enkephalins
TI  - The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders
TY  - research article
ER  -