TY  - JOUR
AU  - Vela-Sebastián, Ana
AU  - López-Gallardo, Ester
AU  - Emperador, Sonia
AU  - Hernández-Ainsa, Carmen
AU  - Pacheu-Grau, David
AU  - Blanco, Ignacio
AU  - Ros, Andrea
AU  - Pascual-Benito, Ester
AU  - Rabaneda-Lombarte, Neus
AU  - Presas-Rodríguez, Silvia
AU  - García-Robles, Pilar
AU  - Montoya, Julio
AU  - Ruiz-Pesini, Eduardo
PY  - 2022
DO  - 10.1111/cge.14189
UR  - http://hdl.handle.net/10668/19927
T2  - Clinical genetics
AB  - Leber hereditary optic neuropathy is a mitochondrial disease mainly due to pathologic mutations in mitochondrial genes related to the respiratory complex I of the oxidative phosphorylation system. Genetic, physiological, and environmental factors...
LA  - en
KW  - LHON
KW  - mtDNA
KW  - mutation
KW  - tRNA
KW  - DNA, Mitochondrial
KW  - Electron Transport Complex I
KW  - Humans
KW  - Mutation
KW  - Optic Atrophy, Hereditary, Leber
KW  - RNA, Transfer
TI  - Toxic and nutritional factors trigger Leber hereditary optic neuropathy due to a mitochondrial tRNA mutation.
TY  - research article
VL  - 102
ER  -