TY - JOUR AU - Granados-Duran, Pablo AU - Lopez-Avalos, Maria Dolores AU - Hughes, Timothy R AU - Johnson, Krista AU - Morgan, B Paul AU - Tamburini, Paul P AU - Fernandez-Llebrez, Pedro AU - Grondona, Jesus M PY - 2016 DO - 10.1186/s12974-016-0576-9 UR - http://hdl.handle.net/10668/10111 T2 - Journal of neuroinflammation AB - In the rat brain, a single intracerebroventricular injection of neuraminidase from Clostridium perfringens induces ependymal detachment and death. This injury occurs before the infiltration of inflammatory blood cells; some reports implicate the... LA - EN PB - BioMed Central Ltd. KW - Anti-C5 KW - Brain ventricles KW - C6-deficient rats KW - Complement system KW - Ependymal cells KW - Inflammation KW - Neuraminidase KW - Animals KW - Cerebral Ventriculitis KW - Complement C5 KW - Complement C6 KW - Neuraminidase KW - Rats TI - Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. TY - research article VL - 13 ER -