TY - JOUR AU - Fraile-Ribot, Pablo A. AU - Zamorano, Laura AU - Orellana, Rocio AU - Del Barrio-Tofiño, Ester AU - Sanchez-Diener, Irina AU - Cortes-Lara, Sara AU - Lopez-Causape, Carla AU - Cabot, Gabriel AU - Bou, German AU - Martinez-Martinez, Luis AU - Oliver, Antonio PY - 2019 DO - 10.1128/AAC.02165-19 UR - http://hdl.handle.net/10668/14708 T2 - Antimicrobial Agents and Chemotherapy AB - Imipenem and imipenem-relebactam MICs were determined for 1,445 Pseudomonas aeruginosa clinical isolates and a large panel of isogenic mutants showing the most relevant mutation-driven β-lactam resistance mechanisms. Imipenem-relebactam showed the... LA - en PB - ASM Journals KW - Pseudomonas aeruginosa KW - Antibiotic resistance KW - Extensively drug resistant KW - Imipenem-relebactam KW - Multidrug resistance KW - Whole-genome sequencing KW - β-lactam resistance mechanisms KW - Anti-Bacterial agents KW - Azabicyclo compounds KW - Colistin KW - Humans KW - Imipenem KW - Mutation KW - Pseudomonas infections KW - Pseudomonas aeruginosa KW - beta-Lactam Resistance KW - beta-Lactamases TI - Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants. TY - research article VL - 64 ER -