Restless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise.

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dc.contributor.authorLamberti, Nicola
dc.contributor.authorLópez-Soto, Pablo Jesús
dc.contributor.authorRodríguez-Borrego, María Aurora
dc.contributor.authorStraudi, Sofia
dc.contributor.authorBasaglia, Nino
dc.contributor.authorZamboni, Paolo
dc.contributor.authorManfredini, Roberto
dc.contributor.authorManfredini, Fabio
dc.date.accessioned2025-01-07T17:18:41Z
dc.date.available2025-01-07T17:18:41Z
dc.date.issued2019-09-06
dc.description.abstractRestless leg syndrome (RLS) disrupts sleep, affecting the quality of life of patients with various chronic diseases. We assessed the prevalence of RLS in peripheral artery disease (PAD) patients and the effects of a pain-free exercise program. A total of 286 patients with claudication were enrolled in a home-based low-intensity exercise program prescribed at the hospital. RLS was determined through standardized questions. Hemodynamics, degree of calf deoxygenation, and mobility were assessed using the ankle-brachial-index, a treadmill test assisted by near-infrared spectroscopy and the 6-min walk test, respectively. During hospital visits, persistence of RLS, adherence to exercise, hemodynamics, and mobility were assessed. At the enrollment, 101 patients (35%) presented RLS, with higher prevalence among females (p = 0.032). Compared to RLS-free patients, they showed similar hemodynamics but more severe calf deoxygenation (p
dc.identifier.doi10.3390/jcm8091403
dc.identifier.issn2077-0383
dc.identifier.pmcPMC6780675
dc.identifier.pmid31500156
dc.identifier.pubmedURLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6780675/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2077-0383/8/9/1403/pdf?version=1568337927
dc.identifier.urihttps://hdl.handle.net/10668/28314
dc.issue.number9
dc.journal.titleJournal of clinical medicine
dc.journal.titleabbreviationJ Clin Med
dc.language.isoen
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)
dc.organizationSAS - Hospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)
dc.pubmedtypeJournal Article
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectexercise therapy
dc.subjectnear-infrared
dc.subjectperipheral artery disease
dc.subjectrehabilitation
dc.subjectrestless leg syndrome
dc.subjectspectroscopy
dc.titleRestless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number8

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