Comparative analysis of the effectiveness and tolerance of intra-articular injection of platelet rich plasma vs hyaluronic acid and non-arthroscopic joint lavage in patientswith knee osteoarthritis

dc.conference.dateJUN 12-15, 2019
dc.conference.titleAnnual European Congress of Rheumatology (EULAR)
dc.contributor.authorOrtega-Castro, Rafaela
dc.contributor.authorSegura, Rocio
dc.contributor.authorCalvo-Gutierrez, Jerusalem
dc.contributor.authorEspino-Garcia, Rocio
dc.contributor.authorCastro-Villegas, Maria del Carmen
dc.contributor.authorEscudero-Contreras, Alejandro
dc.contributor.authorCaracuel-Ruiz, Miguel A.
dc.contributor.authorPineda-Lourdes, Ladehesa
dc.contributor.authorRuiz-Vilchez, Desiree
dc.contributor.authorRomero-Gomez, Montserrat
dc.contributor.authorCarreto-Font, Pilar
dc.contributor.authorCollantes-Estevez, Eduardo
dc.contributor.authorUgalde-Pilar, Font
dc.contributor.authoraffiliation[Ortega Castro, Rafaela] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Segura, Rocio] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Calvo Gutierrez, Jerusalem] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Castro Villegas, Maria del Carmen] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Escudero Contreras, Alejandro] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Caracuel-Ruiz, Miguel A.] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Pineda Lourdes, Ladehesa] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Ruiz-Vilchez, Desiree] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Romero-Gomez, Montserrat] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Collantes Estevez, Eduardo] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Ugalde Pilar, Font] Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Clin Management Unit Rheumatol, Cordoba, Spain
dc.contributor.authoraffiliation[Espino-Garcia, Rocio] Univ Cordoba, Reina Sofia Hosp, Cordoba, Spain
dc.contributor.authoraffiliation[Carreto-Font, Pilar] Tudela Duero Clin East Area, Valladolid, Spain
dc.date.accessioned2025-01-07T13:28:46Z
dc.date.available2025-01-07T13:28:46Z
dc.date.issued2022-05-11
dc.description.abstractBackground: Knee Osteoarthritis (KOA) is a common condition associated with pain and morbidity. The impact of this pathology makes it necessary to develop new procedures for joint regeneration. Regenerative treatments such as platelet-rich plasma (PRP) are being proposed as a safe alternative, capable of regenerating damaged tissues and improving the quality of life, reducing the need for surgical procedures (1-4). Objectives: To compare the effectiveness of PRP treatment vs Hyaluronic Acid (HA) and Non-Arthroscopic Joint Lavage (NAJL) in patients with KOA. Methods: It was performed a prospective, 3-months observational study of 51 patients with KOA, from the OA clinic of the Reina Sofía Hospital of Córdoba. Patients were treated according to clinical practice in 1 of the 3 treatment arms (PRP, HA, NAJL). Pain and disability were evaluated using Visual Analogue Scale (VAS) of joint pain, WOMAC and OARSI. We compared the baseline data using simple ANOVA and chi-squared tests and the intra- and inter-group differences before and after treatment (0, 1 and 3 months) using the mixed ANOVA test. All comparisons were bilateral considering p≤0.05 as a significant result. Results: 51 patients were enrolled, of which 52.9% were female. The average age (±SD) was 58.47 ± 7.48 years.
dc.description.versionSi
dc.identifier.citationCastro RO, Segura R, Gutierrez JC, et alAB0100Comparative analysis of the effectiveness and tolerance of intra-articular injection of platelet rich plasma vs hyaluronic acid and non-arthroscopic joint lavage in patientswith knee osteoarthritis. Annals of the Rheumatic Diseases 2019;78:1511-1512
dc.identifier.doi10.1136/annrheumdis-2019-eular.6598
dc.identifier.essn1468-2060
dc.identifier.issn0003-4967
dc.identifier.unpaywallURLhttps://ard.bmj.com/content/annrheumdis/78/Suppl_2/1511.2.full.pdf
dc.identifier.urihttps://hdl.handle.net/10668/25563
dc.identifier.wosID472207104429
dc.issue.number2
dc.journal.titleAnnals of the rheumatic diseases
dc.journal.titleabbreviationAnn. rheum. dis.
dc.language.isoen
dc.organizationSAS - Hospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)
dc.page.number1511-1512
dc.provenanceRealizada la curación de contenido 03/07/2025
dc.publisherBmj publishing group
dc.relation.publisherversionhttps://ard.bmj.com/content/78/Suppl_2/1511.2
dc.rights.accessRightsRestricted Access
dc.subjectOsteoarthritis, Knee
dc.subjectQuality of Life
dc.subjectArthralgia
dc.subjectRegeneration
dc.subject.decsOsteoartritis de rodilla
dc.subject.decsPlasma rico en plaquetas
dc.subject.decsÁcido hialurónico
dc.subject.decsLavado articular no artroscópico
dc.subject.decsEscala analógica visual
dc.subject.decsDiscapacidad funcional
dc.subject.meshProspective Studies
dc.subject.meshTherapeutic Irrigation
dc.subject.meshVisual Analog Scale
dc.subject.meshPain
dc.titleComparative analysis of the effectiveness and tolerance of intra-articular injection of platelet rich plasma vs hyaluronic acid and non-arthroscopic joint lavage in patientswith knee osteoarthritis
dc.typeconference output
dc.type.hasVersionVoR
dc.volume.number78
dc.wostypeMeeting Abstract

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