Antiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation Registry

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dc.contributor.authorSantoro, Francesco
dc.contributor.authorNunez-Gil, Ivan Javier
dc.contributor.authorVitale, Enrica
dc.contributor.authorViana-Llamas, Maria C.
dc.contributor.authorReche-Martinez, Begona
dc.contributor.authorRomero-Pareja, Rodolfo
dc.contributor.authorFeltez Guzman, Gisela
dc.contributor.authorFernandez Rozas, Inmaculada
dc.contributor.authorUribarri, Aitor
dc.contributor.authorBecerra-Munoz, Victor Manuel
dc.contributor.authorAlfonso-Rodriguez, Emilio
dc.contributor.authorGarcia-Aguado, Marcos
dc.contributor.authorHuang, Jia
dc.contributor.authorOrtega-Armas, Maria Elizabeth
dc.contributor.authorGarcia Prieto, Juan F.
dc.contributor.authorCorral Rubio, Eva Maria
dc.contributor.authorUgo, Fabrizio
dc.contributor.authorBianco, Matteo
dc.contributor.authorMulet, Alba
dc.contributor.authorRaposeiras-Roubin, Sergio
dc.contributor.authorJativa Mendez, Jorge Luis
dc.contributor.authorEspejo Paeres, Carolina
dc.contributor.authorAlbarran, Adrian Rodriguez
dc.contributor.authorMarin, Francisco
dc.contributor.authorGuerra, Federico
dc.contributor.authorAkin, Ibrahim
dc.contributor.authorCortese, Bernardo
dc.contributor.authorRamakrishna, Harish
dc.contributor.authorMacaya, Carlos
dc.contributor.authorFernandez-Ortiz, Antonio
dc.contributor.authorBrunetti, Natale Daniele
dc.contributor.authoraffiliation[Santoro, Francesco] Univ Foggia, Dept Med & Surg Sci, Foggia, Italy
dc.contributor.authoraffiliation[Vitale, Enrica] Univ Foggia, Dept Med & Surg Sci, Foggia, Italy
dc.contributor.authoraffiliation[Brunetti, Natale Daniele] Univ Foggia, Dept Med & Surg Sci, Foggia, Italy
dc.contributor.authoraffiliation[Nunez-Gil, Ivan Javier] San Carlos Univ Hosp, Dept Cardiol, Madrid, Spain
dc.contributor.authoraffiliation[Macaya, Carlos] San Carlos Univ Hosp, Dept Cardiol, Madrid, Spain
dc.contributor.authoraffiliation[Viana-Llamas, Maria C.] Hosp Gen Univ Guadalajara, Dept Intens Med, Guadalajara, Spain
dc.contributor.authoraffiliation[Reche-Martinez, Begona] Hosp Univ La Paz, Dept Emergency, Madrid, Spain
dc.contributor.authoraffiliation[Romero-Pareja, Rodolfo] Hosp Univ Getafe, Dept Emergency, Getafe, Spain
dc.contributor.authoraffiliation[Feltez Guzman, Gisela] Hosp Nuestra Senora Amer, Dept Cardiol, Madrid, Spain
dc.contributor.authoraffiliation[Fernandez Rozas, Inmaculada] Hosp Univ Severo Ochoa, Dept Cardiol, Leganes, Spain
dc.contributor.authoraffiliation[Uribarri, Aitor] Hosp Clin Univ Valladolid, Dept Cardiol, Valladolid, Spain
dc.contributor.authoraffiliation[Becerra-Munoz, Victor Manuel] Hosp Clin Univ Virgen Victoria, Dept Cardiol, Malaga, Spain
dc.contributor.authoraffiliation[Alfonso-Rodriguez, Emilio] Inst Cardiol & Cardiovasc Surg, Dept Cardiol, Havana, Cuba
dc.contributor.authoraffiliation[Garcia-Aguado, Marcos] Puerta Hierro Univ Hosp Majadahonda, Dept Cardiol, Majadahonda, Spain
dc.contributor.authoraffiliation[Huang, Jia] Southern Univ Sci & Technol, Dept Cardiol, Affiliated Hosp 2, Shenzhen, Peoples R China
dc.contributor.authoraffiliation[Ortega-Armas, Maria Elizabeth] Hosp Gen Norte Guayaquil, Dept Cardiol, Guayaquil, Ecuador
dc.contributor.authoraffiliation[Garcia Prieto, Juan F.] Hosp Manises, Dept Emergency Med, Valencia, Spain
dc.contributor.authoraffiliation[Corral Rubio, Eva Maria] Hosp Univ Infanta Sofia, Dept Anesthesiol, Madrid, Spain
dc.contributor.authoraffiliation[Ugo, Fabrizio] Sant Andrea Hosp, Dept Cardiol, Vercelli, Italy
dc.contributor.authoraffiliation[Bianco, Matteo] San Luigi Gonzaga Univ Hosp, Orbassano & Rivoli Infermi Hosp, Div Cardiol, Rivoli, Italy
dc.contributor.authoraffiliation[Mulet, Alba] Hosp Clin Valencia, Dept Lung Dis, Valencia, Spain
dc.contributor.authoraffiliation[Raposeiras-Roubin, Sergio] Univ Hosp Alvaro Cunqueiro, Dept Cardiol, Vigo, Spain
dc.contributor.authoraffiliation[Jativa Mendez, Jorge Luis] Hosp Especialidades Fuerzas Armadas, Dept Cardiol, Quito, Ecuador
dc.contributor.authoraffiliation[Espejo Paeres, Carolina] Hosp Univ Principe Asturias, Dept Cardiol, Madrid, Spain
dc.contributor.authoraffiliation[Albarran, Adrian Rodriguez] Hosp Univ Juan Ramon Jimenez, Dept Cardiol, Huelva, Spain
dc.contributor.authoraffiliation[Marin, Francisco] Univ Murcia, Hosp Clin Univ Virgen Arrixaca, IMIB Arrixaca, Dept Cardiol, Murcia, Spain
dc.contributor.authoraffiliation[Guerra, Federico] Marche Polytech Univ, Univ Hosp Osped Riuniti, Cardiol & Arrhythmol Dept, Ancona, Italy
dc.contributor.authoraffiliation[Akin, Ibrahim] Univ Mannheim, Fac Med, Dept Med 1, Mannheim, Germany
dc.contributor.authoraffiliation[Cortese, Bernardo] Clin San Carlo, Dept Cardiol, Milan, Italy
dc.contributor.authoraffiliation[Ramakrishna, Harish] Mayo Clin, Dept Cardiovasc & Thorac Anesthesiol, Rochester, MN USA
dc.contributor.authoraffiliation[Fernandez-Ortiz, Antonio] San Carlos Univ Hosp, Dept Cardiol, Madrid, Spain
dc.date.accessioned2025-01-07T15:06:42Z
dc.date.available2025-01-07T15:06:42Z
dc.date.issued2021-10-05
dc.description.abstractBackground Standard therapy for COVID-19 is continuously evolving. Autopsy studies showed high prevalence of platelet-fibrin-rich microthrombi in several organs. The aim of the study was therefore to evaluate the safety and efficacy of antiplatelet therapy (APT) in hospitalised patients with COVID-19 and its impact on survival.Methods 7824 consecutive patients with COVID-19 were enrolled in a multicentre international prospective registry (Health Outcome Predictive Evaluation-COVID-19 Registry). Clinical data and in-hospital complications were recorded. Data on APT, including aspirin and other antiplatelet drugs, were obtained for each patient.Results During hospitalisation, 730 (9%) patients received single APT (93%, n=680) or dual APT (7%, n=50). Patients treated with APT were older (74 +/- 12 years vs 63 +/- 17 years, p
dc.identifier.doi10.1136/heartjnl-2021-319552
dc.identifier.essn1468-201X
dc.identifier.issn1355-6037
dc.identifier.pmid34611045
dc.identifier.unpaywallURLhttps://heart.bmj.com/content/heartjnl/108/2/130.full.pdf
dc.identifier.urihttps://hdl.handle.net/10668/26896
dc.identifier.wosID722678600001
dc.issue.number2
dc.journal.titleHeart
dc.journal.titleabbreviationHeart
dc.language.isoen
dc.organizationSAS - Hospital Universitario Virgen de la Victoria
dc.page.number130-136
dc.publisherBmj publishing group
dc.rights.accessRightsopen access
dc.subjectCOVID-19
dc.subjectpharmacology
dc.subjectclinical
dc.subjectCoronavirus disease 2019
dc.titleAntiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation Registry
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number108
dc.wostypeArticle

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