Clinical-pathological characteristics and short-term follow-up associated with proliferation, apoptosis and angiogenesis in a prospective cohort of patients with colorectal tumours.

Simple item page
dc.contributor.authorRedondo, Maximino
dc.contributor.authorAbitei, Cristina
dc.contributor.authorTéllez, Teresa
dc.contributor.authorFúnez, Rafael
dc.contributor.authorPereda, Teresa
dc.contributor.authorRodrigo, Isabel
dc.contributor.authorBetancourt, Ana M
dc.contributor.authorGarcía-Aranda, Marilina
dc.contributor.authorRueda, Antonio
dc.contributor.authorMartínez García, Rafael Cayetano
dc.contributor.authorMorales Suarez-Varela, María Manuela
dc.contributor.authorZabalza, Iñaki
dc.contributor.authorSánchez Del Charco, Matilde
dc.contributor.authorBorrero Martín, Juan José
dc.contributor.authorGarcía Del Moral, Raimundo
dc.contributor.authorEscobar, Antonio
dc.contributor.authorQuintana, JoséMaría
dc.contributor.authorRivas-Ruiz, Francisco
dc.contributor.authorREDISSEC-CARESS/CCR group
dc.date.accessioned2025-01-07T15:07:44Z
dc.date.available2025-01-07T15:07:44Z
dc.date.issued2019
dc.description.abstractWe investigate the clinical and pathological features related to variations in colorectal tumour apoptosis, proliferation and angiogenesis and the influence of the latter in short-term mortality (2 years); 551 tumour samples from a prospective cohort of patients with colorectal cancer were examined and tumour biology markers were determined as follows: percentage of apoptotic cells, by the terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling technique; Ki-67 antigen, as a cell proliferation marker and density of microvessels (as a marker of angiogenesis). An increase in the percentage of cellular apoptosis is significantly related to the presence of poorly differentiated tumours, with vascular invasion (p 
dc.identifier.doi10.1177/1010428319835684
dc.identifier.essn1423-0380
dc.identifier.pmid30957671
dc.identifier.unpaywallURLhttps://journals.sagepub.com/doi/pdf/10.1177/1010428319835684
dc.identifier.urihttps://hdl.handle.net/10668/26902
dc.issue.number4
dc.journal.titleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
dc.journal.titleabbreviationTumour Biol
dc.language.isoen
dc.organizationSAS - Hospital Universitario Virgen de la Victoria
dc.page.number1010428319835684
dc.pubmedtypeJournal Article
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectCell proliferation
dc.subjectKi-67 marker
dc.subjectangiogenesis
dc.subjectapoptosis
dc.subjectcolorectal neoplasms
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshApoptosis
dc.subject.meshBiomarkers, Tumor
dc.subject.meshCell Proliferation
dc.subject.meshColorectal Neoplasms
dc.subject.meshDisease-Free Survival
dc.subject.meshEndoglin
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshHumans
dc.subject.meshKi-67 Antigen
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNeovascularization, Pathologic
dc.subject.meshPrognosis
dc.titleClinical-pathological characteristics and short-term follow-up associated with proliferation, apoptosis and angiogenesis in a prospective cohort of patients with colorectal tumours.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number42

Files

Collections

SAS - Hospital Universitario Virgen de la Victoria

© 2023 – Repositorio Institucional de Salud de Andalucía - Fundación Pública Andaluza Progreso y Salud - Consejería de Salud y Consumo de la Junta de Andalucía