Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients.
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2019-06-18
Authors
Garrido-Hermosilla, Antonio Manuel
Méndez-Muros, Mariola
Gutiérrez-Sánchez, Estanislao
Morales-Portillo, Cristóbal
Díaz-Granda, María Jesús
Esteban-González, Eduardo
Relimpio-López, Isabel
Martínez-Brocca, María Asunción
Rodríguez-de-la-Rúa-Franch, Enrique
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Abstract
To assess the relationship between choroidal thickness and renal function in diabetic patients. Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy; retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography; presence of cystic macular edema; and ocular axial length (AXL). Lab-test parameters included: glycated hemoglobin (HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate. A significant negative correlation was mainly observed between several choroidal thicknesses, age (P Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-naïve diabetic patients.
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Keywords
choroidal thickness, diabetes mellitus, renal function, spectral-domain optical coherence tomography, swept-source optical coherence tomography