Enhanced depth OCT imaging of the lamina cribrosa for 24 hours.
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2017-02-18
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Naranjo-Bonilla, Pedro
Giménez-Gómez, Rafael
Ríos-Jiménez, David
Varas-Fabra, María Luísa
Muñoz-Villanueva, María Del Carmen
García-Catalán, Rocío
Font-Ugalde, Pilar
Poblador-Fernández, María Soledad
Lancho-Alonso, José Luís
Gallardo-Galera, José María
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Abstract
The lamina cribrosa thickness (LCT) could be affected by dynamic changes in its structure. Using Spectral-domain-optical coherence tomography (SD-OCT), we have studied the behaviour of the laminar region in 14 young subjects over 24h. Significant changes in LCT were observed, depending on the time at which the measurement was taken, with the maximum thickness being observed at 7.30 p.m., and the minimum at 7.30 a.m. This finding could suggests a circadian pattern in the LCT thickness in healthy subjects, which could have implications for the classification, diagnosis and prognosis of both normal and glaucomatous subjects.
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glaucoma, lamina cribrosa, laminar region, optical coherence tomography, twenty-four-hours