Coinfection with HIV and hepatitis C virus in 229 children and young adults living in Europe

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dc.contributor.authorThorne, Claire
dc.contributor.authorTurkova, Anna
dc.contributor.authorIndolfi, Giuseppe
dc.contributor.authorVenturini, Elisabetta
dc.contributor.authorGiaquinto, Carlo
dc.contributor.authorGoetghebuer, Tessa
dc.contributor.authorHainaut, Marc
dc.contributor.authorVan der Kelen, Evelyne
dc.contributor.authorKoenigs, Christoph
dc.contributor.authorMantzsch, Kathleen
dc.contributor.authorBaumann, Ulrich
dc.contributor.authorde Martino, Maurizio
dc.contributor.authorGalli, Luisa
dc.contributor.authorGiacomet, Vania
dc.contributor.authorNicolini, Laura Ambra
dc.contributor.authorDel Puente, Filippo
dc.contributor.authorGabiano, Clara
dc.contributor.authorGuarino, Alfredo
dc.contributor.authorMartinazzi, Silvia
dc.contributor.authorMiniaci, Angela
dc.contributor.authorDobsz, Sabina
dc.contributor.authorMarczynska, Magdalena
dc.contributor.authorEne, Luminita
dc.contributor.authorDuiculescu, Dan
dc.contributor.authorMiloenko, Milana
dc.contributor.authorDodonov, Konstantin
dc.contributor.authorLatysheva, Inga
dc.contributor.authorVoronin, Evgeny
dc.contributor.authorRojo, Pablo
dc.contributor.authorTomas Ramos, Jose
dc.contributor.authorNavarro, Marisa
dc.contributor.authorJimenez de Ory, Santiago
dc.contributor.authorSainz, Talia
dc.contributor.authorMellado, Maria J.
dc.contributor.authorGarcia, Miluca
dc.contributor.authorPerez, Carlos
dc.contributor.authorMoreno, David
dc.contributor.authorNunez, Esmeralda
dc.contributor.authorGracia, Mercedes
dc.contributor.authorTerol, Pedro
dc.contributor.authorNeth, Olaf
dc.contributor.authorFalcon, Lola
dc.contributor.authorOtero, Carmen
dc.contributor.authorRincon, Elena
dc.contributor.authorLopez, Carmen
dc.contributor.authorLuis Santos, Juan
dc.contributor.authorCouceiro, Jose
dc.contributor.authorNoguera-Julian, Antoni
dc.contributor.authorFortuny, Claudia
dc.contributor.authorSoler-Palacin, Pere
dc.contributor.authorEspiau, Maria
dc.contributor.authorMur, Antonio
dc.contributor.authorColl, Maria T.
dc.contributor.authorValmanya, Maria T.
dc.contributor.authorMayol, Luis
dc.contributor.authorMendez, Maria J.
dc.contributor.authorRodrigo, Carlos
dc.contributor.authorEscribano, Joaquin
dc.contributor.authorRius, Neus
dc.contributor.authorRovira, Nuria
dc.contributor.authorCalavia, Olga
dc.contributor.authorGarcia, Lourdes
dc.contributor.authorPineda, Valenti
dc.contributor.authorSoriano-Arandes, Antoni
dc.contributor.authorRudin, Christoph
dc.contributor.authorDuppenthaler, Andrea
dc.contributor.authorJudd, Ali
dc.contributor.authorMalyuta, Ruslan
dc.contributor.authorVolokha, Alla
dc.contributor.authorRaus, Irina
dc.contributor.authorKaleeva, T.
dc.contributor.authorBaryshnikova, Y.
dc.contributor.authorSoloha, Svetlana
dc.contributor.authorBashkatova, N.
dc.contributor.authorGlutshenko, O.
dc.contributor.authorRuban, Z.
dc.contributor.authorPrimak, Natalia
dc.contributor.authorKiseleva, Galina
dc.contributor.authorEuropean Paediat HIV HCV
dc.contributor.authoraffiliation[Thorne, Claire] UCL, Inst Child Hlth, London, England
dc.contributor.authoraffiliation[Turkova, Anna] UCL, MRC Clin Trials Unit, London, England
dc.contributor.authoraffiliation[Indolfi, Giuseppe] Meyer Childrens Univ Hosp Florence, Florence, Italy
dc.contributor.authoraffiliation[Venturini, Elisabetta] Meyer Childrens Univ Hosp Florence, Florence, Italy
dc.contributor.authoraffiliation[Giaquinto, Carlo] Univ Padua, I-35100 Padua, Italy
dc.contributor.authoraffiliation[Giacomet, Vania] Univ Milan, Luigi Sacco Hosp, I-20122 Milan, Italy
dc.contributor.authoraffiliation[Nicolini, Laura Ambra] Univ Genoa, IRCCS AOU San Martino IST, I-16126 Genoa, Italy
dc.contributor.authoraffiliation[Del Puente, Filippo] Univ Genoa, IRCCS AOU San Martino IST, I-16126 Genoa, Italy
dc.contributor.authoraffiliation[Miloenko, Milana] RHID, St Petersburg, Russia
dc.contributor.authoraffiliation[Dodonov, Konstantin] RHID, St Petersburg, Russia
dc.contributor.authoraffiliation[Latysheva, Inga] RHID, St Petersburg, Russia
dc.contributor.authoraffiliation[Voronin, Evgeny] RHID, St Petersburg, Russia
dc.contributor.authoraffiliation[Rojo, Pablo] Univ Complutense, Hosp 12 Octubre, Madrid, Spain
dc.contributor.authoraffiliation[Tomas Ramos, Jose] Hosp Clin Barcelona, Barcelona, Spain
dc.contributor.authoraffiliation[Navarro, Marisa] Gregorio Maranon Hosp, Madrid, Spain
dc.contributor.authoraffiliation[Jimenez de Ory, Santiago] Gregorio Maranon Hosp, Madrid, Spain
dc.contributor.authoraffiliation[Sainz, Talia] Gregorio Maranon Hosp, Madrid, Spain
dc.contributor.authoraffiliation[Mellado, Maria J.] Hosp La Paz, Madrid, Spain
dc.contributor.authoraffiliation[Garcia, Miluca] Hosp La Paz, Madrid, Spain
dc.contributor.authoraffiliation[Otero, Carmen] Hosp La Paz, Madrid, Spain
dc.contributor.authoraffiliation[Rincon, Elena] Hosp La Paz, Madrid, Spain
dc.contributor.authoraffiliation[Perez, Carlos] Hosp Cabuenes, Gijon, Asturias, Spain
dc.contributor.authoraffiliation[Moreno, David] Hosp Carlos Haya, Malaga, Spain
dc.contributor.authoraffiliation[Nunez, Esmeralda] Hosp Carlos Haya, Malaga, Spain
dc.contributor.authoraffiliation[Gracia, Mercedes] Hosp Clin Zaragoza, Zaragoza, Spain
dc.contributor.authoraffiliation[Terol, Pedro] Hosp Virgen Macarena, Seville, Spain
dc.contributor.authoraffiliation[Neth, Olaf] Hosp Virgen Rocio, Seville, Spain
dc.contributor.authoraffiliation[Falcon, Lola] Hosp Virgen Rocio, Seville, Spain
dc.contributor.authoraffiliation[Lopez, Carmen] Hosp Castellon, Castellon de La Plana, Spain
dc.contributor.authoraffiliation[Luis Santos, Juan] Hosp Virgen Nieves, Granada, Spain
dc.contributor.authoraffiliation[Couceiro, Jose] Hosp Pontevedra, Pontevedra, Spain
dc.contributor.authoraffiliation[Noguera-Julian, Antoni] Univ Barcelona, Hosp St Joan Deu, E-08007 Barcelona, Spain
dc.contributor.authoraffiliation[Judd, Ali] UCL, MRC Clin Trials Unit, London WC1E 6BT, England
dc.contributor.authoraffiliation[Malyuta, Ruslan] PPAI, Odessa, Ukraine
dc.contributor.authoraffiliation[Volokha, Alla] Shupyk Natl Med Acad Postgrad Educ, Kiev, Ukraine
dc.contributor.authoraffiliation[Raus, Irina] Kiev City Ctr HIV AIDS, Kiev, Ukraine
dc.contributor.authoraffiliation[Kaleeva, T.] Odessa Reg Ctr HIV AIDS, Odessa, Ukraine
dc.contributor.authoraffiliation[Baryshnikova, Y.] Odessa Reg Ctr HIV AIDS, Odessa, Ukraine
dc.contributor.authoraffiliation[Soloha, Svetlana] Donetsk Reg Ctr HIV AIDS, Donetsk, Ukraine
dc.contributor.authoraffiliation[Bashkatova, N.] Mariupol AIDS Ctr, Mariupol, Ukraine
dc.contributor.authoraffiliation[Glutshenko, O.] Mykolaiv Reg Ctr HIV AIDS, Mykolaiv, Ukraine
dc.contributor.authoraffiliation[Ruban, Z.] Mykolaiv Reg Ctr HIV AIDS, Mykolaiv, Ukraine
dc.contributor.authoraffiliation[Primak, Natalia] Kryvyi Rih City Ctr HIV AIDS, Kryvyi Rih, Ukraine
dc.contributor.authoraffiliation[Kiseleva, Galina] Simferopol Ctr HIV AIDS, Simferopol, Ukraine
dc.contributor.authoraffiliation[de Martino, Maurizio] Meyer Childrens Univ Hosp Florence, Florence, Italy
dc.contributor.authoraffiliation[Galli, Luisa] Meyer Childrens Univ Hosp Florence, Florence, Italy
dc.contributor.funderEU under EuroCoord
dc.contributor.funderJanssen
dc.date.accessioned2025-01-07T14:26:31Z
dc.date.available2025-01-07T14:26:31Z
dc.date.issued2017-01-02
dc.description.abstractObjective:To characterize children, adolescents and young adults infected with HIV/hepatitis C virus (HCV) vertically or before age of 18 years and living in Europe regarding mode of acquisition, HCV genotype, clinical status and treatment.Design:Retrospective, cross-sectional study using pooled data from 11 European paediatric HIV cohorts.Methods:Patients aged more than 18 months and less than 25 years, with HIV/HCV acquired vertically or in childhood, were included. Anonymized individual patient data were collected using a standard protocol and modified HIV Cohorts Data Exchange Protocol.Results:Of 229 patients included, 142 (62%) had vertically acquired infection. Median age at last follow-up was 16.2 years. Most children had HCV genotype 1 (101/184, 55%) or 3 (57/184, 31%). One-fifth (46/214) had a previous AIDS diagnosis (data missing on prior AIDS diagnoses for 15). At their last clinic visit, 70% (145/208) had no/mild immunosuppression (Centers for Disease Control and Prevention stage 1), and 131 of 179 on antiretroviral therapy had undetectable HIV RNA (assay thresholds varied from
dc.identifier.doi10.1097/QAD.0000000000001285
dc.identifier.essn1473-5571
dc.identifier.issn0269-9370
dc.identifier.pmid27898593
dc.identifier.unpaywallURLhttps://iris.unige.it/bitstream/11567/884435/2/Coinfection_with_HIV_and_hepatitis_C_virus_in_229.14.pdf
dc.identifier.urihttps://hdl.handle.net/10668/26391
dc.identifier.wosID390240700014
dc.issue.number1
dc.journal.titleAids
dc.journal.titleabbreviationAids
dc.language.isoen
dc.organizationSAS - Hospital Universitario Virgen de las Nieves
dc.organizationSAS - Hospital Universitario Regional de Málaga
dc.organizationSAS - Hospital Universitario Virgen del Rocío
dc.organizationSAS - Hospital Universitario Virgen Macarena
dc.page.number127-135
dc.publisherLippincott williams & wilkins
dc.rights.accessRightsopen access
dc.subjectcoinfection
dc.subjecthepatitis C
dc.subjectHIV
dc.subjectpaediatric
dc.subjectvertical infection
dc.subjectHuman-immunodeficiency-virus
dc.subjectSimple noninvasive index
dc.subjectAntiretroviral therapy
dc.subjectPegylated interferon
dc.subjectFibrosis progression
dc.subjectSt-petersburg
dc.subjectLiver
dc.subjectImpact
dc.subjectTransmission
dc.subjectAdolescents
dc.titleCoinfection with HIV and hepatitis C virus in 229 children and young adults living in Europe
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number31
dc.wostypeArticle

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