Age at onset in axial spondyloarthritis around the world: data from the Assessment in SpondyloArthritis international Society Peripheral Involvement in Spondyloarthritis study
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Date
2021-09-22
Authors
Boel, Anne
Lopez-Medina, Clementina
van der Heijde, Desiree M. F. M.
van Gaalen, Floris Alexander
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Oxford univ press
Abstract
Objective Age at onset is useful in identifying chronic back patients at an increased risk of axial SpA (axSpA). However, the majority of data on which the criterion of age at onset Methods Analyses were applied to patients from 24 countries across the world with an axSpA diagnosis and known age at onset of axial complaints. Cumulative probability plots were used to display the cumulative distribution of age at onset of axial symptoms. Linear regression models were built to assess the effect of HLA-B27 and gender on age at onset of axial symptoms. Results Of 2579 axSpA patients, 92% had an age at onset of axial symptoms
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Keywords
axial spondyloarthritis, age at onset, HLA-B27, gender, Inflammatory back-pain, Ankylosing-spondylitis, Classification criteria, Positive patients, Disease onset, Diagnosis