Hematuria Is Associated with More Severe Acute Tubulointerstitial Nephritis.
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2020-07-07
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Esteras, Raquel
Fox, Jonathan G
Geddes, Colin C
Mackinnon, Bruce
Ortiz, Alberto
Moreno, Juan Antonio
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Abstract
Acute tubulointerstitial nephritis (ATIN) is a common cause of acute kidney injury. Although haematuria is a risk factor for the development of renal disease, no previous study has analyzed the significance of haematuria in ATIN. Retrospective, observational analysis of 110 patients with biopsy-proven ATIN was conducted. Results: Haematuria was present in 66 (60%) ATIN patients. A higher percentage of ATIN patients with haematuria had proteinuria than patients without haematuria (89.4% vs. 59.1%, p = 0.001) with significantly higher levels of proteinuria (median (interquartile range) protein:creatinine ratio 902.70 (513-1492) vs. 341.00 (177-734) mg/g, p
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acute kidney injury, acute tubulointerstitial nephritis, chronic kidney disease, haematuria, kidney biopsy, outcomes, proteinuria