Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up

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dc.contributor.authorStrauss, S. J.
dc.contributor.authorFrezza, A. M.
dc.contributor.authorAbecassis, N.
dc.contributor.authorBajpai, J.
dc.contributor.authorBauer, S.
dc.contributor.authorBiagini, R.
dc.contributor.authorBielack, S.
dc.contributor.authorBlay, J. Y.
dc.contributor.authorBolle, S.
dc.contributor.authorBonvalot, S.
dc.contributor.authorBoukovinas, I
dc.contributor.authorBovee, J. V. M. G.
dc.contributor.authorBoye, K.
dc.contributor.authorBrennan, B.
dc.contributor.authorBrodowicz, T.
dc.contributor.authorBuonadonna, A.
dc.contributor.authorde-Alava, E.
dc.contributor.authorDei-Tos, A. P.
dc.contributor.authorDel-Muro, X. Garcia
dc.contributor.authorDufresne, A.
dc.contributor.authorEriksson, M.
dc.contributor.authorFagioli, F.
dc.contributor.authorFedenko, A.
dc.contributor.authorFerraresi, V
dc.contributor.authorFerrari, A.
dc.contributor.authorGaspar, N.
dc.contributor.authorGasperoni, S.
dc.contributor.authorGelderblom, H.
dc.contributor.authorGouin, F.
dc.contributor.authorGrignani, G.
dc.contributor.authorGronchi, A.
dc.contributor.authorHaas, R.
dc.contributor.authorHassan, A. B.
dc.contributor.authorHecker-Nolting, S.
dc.contributor.authorHindi, N.
dc.contributor.authorHohenberger, P.
dc.contributor.authorJoensuu, H.
dc.contributor.authorJones, R. L.
dc.contributor.authorJungels, C.
dc.contributor.authorJutte, P.
dc.contributor.authorKager, L.
dc.contributor.authorKasper, B.
dc.contributor.authorKawai, A.
dc.contributor.authorKopeckova, K.
dc.contributor.authorKrakorova, D. A.
dc.contributor.authorLe-Cesne, A.
dc.contributor.authorLe-Grange, F.
dc.contributor.authorLegius, E.
dc.contributor.authorLeithner, A.
dc.contributor.authorPousa, A. Lopez
dc.contributor.authorMartin-Broto, J.
dc.contributor.authorMerimsky, O.
dc.contributor.authorMessiou, C.
dc.contributor.authorMiah, A. B.
dc.contributor.authorMir, O.
dc.contributor.authorMontemurro, M.
dc.contributor.authorMorland, B.
dc.contributor.authorMorosi, C.
dc.contributor.authorPalmerini, E.
dc.contributor.authorPantaleo, M. A.
dc.contributor.authorPiana, R.
dc.contributor.authorPiperno-Neumann, S.
dc.contributor.authorReichardt, P.
dc.contributor.authorRutkowski, P.
dc.contributor.authorSafwat, A. A.
dc.contributor.authorSangalli, C.
dc.contributor.authorSbaraglia, M.
dc.contributor.authorScheipl, S.
dc.contributor.authorSchoffski, P.
dc.contributor.authorSleijfer, S.
dc.contributor.authorStrauss, D.
dc.contributor.authorHall, K. Sundby
dc.contributor.authorTrama, A.
dc.contributor.authorUnk, M.
dc.contributor.authorvan-de-Sande, M. A. J.
dc.contributor.authorvan-der-Graaf, W. T. A.
dc.contributor.authorvan-Houdt, W. J.
dc.contributor.authorFrebourg, T.
dc.contributor.authorLadenstein, R.
dc.contributor.authorCasali, P. G.
dc.contributor.authorStacchiotti, S.
dc.contributor.authoraffiliation[Strauss, S. J.] Univ Coll London Hosp NHS Fdn Trust UCLH, Dept Oncol, London, England
dc.contributor.authoraffiliation[Le Grange, F.] Univ Coll London Hosp NHS Fdn Trust UCLH, Dept Oncol, London, England
dc.contributor.authoraffiliation[Frezza, A. M.] Fdn IRCCS Ist Nazl Tumori, Dept Canc Med, Milan, Italy
dc.contributor.authoraffiliation[Casali, P. G.] Fdn IRCCS Ist Nazl Tumori, Dept Canc Med, Milan, Italy
dc.contributor.authoraffiliation[Stacchiotti, S.] Fdn IRCCS Ist Nazl Tumori, Dept Canc Med, Milan, Italy
dc.contributor.authoraffiliation[Abecassis, N.] EPE, Inst Portugues Oncol Lisboa Francisco Gentil, Lisbon, Portugal
dc.contributor.authoraffiliation[Bajpai, J.] Homi Bhabha Natl Inst, Tata Mem Ctr, Dept Med Oncol, Mumbai, Maharashtra, India
dc.contributor.authoraffiliation[Bauer, S.] Univ Duisburg Essen, Interdisciplinary Sarcoma Ctr, West German Canc Ctr, Dept Med Oncol, Essen, Germany
dc.contributor.authoraffiliation[Biagini, R.] IRCCS Regina Elena Natl Canc Inst, Dept Oncol Orthoped, Rome, Italy
dc.contributor.authoraffiliation[Bielack, S.] Olga Hosp, Klinikum Stuttgart, Stuttgart, Germany
dc.contributor.authoraffiliation[Hecker-Nolting, S.] Olga Hosp, Klinikum Stuttgart, Stuttgart, Germany
dc.contributor.authoraffiliation[Blay, J. Y.] Ctr Leon Berard, Lyon, France
dc.contributor.authoraffiliation[Blay, J. Y.] UCBL1, Lyon, France
dc.contributor.authoraffiliation[Bolle, S.] Gustave Roussy, Radiat Oncol Dept, Villejuif, France
dc.contributor.authoraffiliation[Bonvalot, S.] Inst Curie, Dept Surg, Paris, France
dc.contributor.authoraffiliation[Boukovinas, I] Bioclin Thessaloniki, Thessaloniki, Greece
dc.contributor.authoraffiliation[Bovee, J. V. M. G.] Leiden Univ Med Ctr, Dept Pathol, Leiden, Netherlands
dc.contributor.authoraffiliation[Boye, K.] Oslo Univ Hosp, Norwegian Radium Hosp, Dept Oncol, Oslo, Norway
dc.contributor.authoraffiliation[Hall, K. Sundby] Oslo Univ Hosp, Norwegian Radium Hosp, Dept Oncol, Oslo, Norway
dc.contributor.authoraffiliation[Brennan, B.] Royal Manchester Childrens Hosp, Paediat Oncol, Manchester, Lancs, England
dc.contributor.authoraffiliation[Brodowicz, T.] Med Univ Wien, Vienna Gen Hosp AKH, Vienna, Austria
dc.contributor.authoraffiliation[Buonadonna, A.] Ctr Riferimento Oncol Aviano, Aviano, Italy
dc.contributor.authoraffiliation[de Alava, E.] Univ Seville, CSIC, Virgen del Rocio Univ Hosp, Inst Biomed Sevilla IBiS,CIBERONC, Seville, Spain
dc.contributor.authoraffiliation[de Alava, E.] Univ Seville, Sch Med, Dept Normal & Pathol Cytol & Histol, Seville, Spain
dc.contributor.authoraffiliation[Dei Tos, A. P.] Azienda Osped Univ Padova, Dept Pathol, Padua, Italy
dc.contributor.authoraffiliation[Sbaraglia, M.] Azienda Osped Univ Padova, Dept Pathol, Padua, Italy
dc.contributor.authoraffiliation[Del Muro, X. Garcia] Hub, Integrated Unit ICO Hosp, Barcelona, Spain
dc.contributor.authoraffiliation[Dufresne, A.] Ctr Leon Berard, Dept Oncol Med, Lyon, France
dc.contributor.authoraffiliation[Eriksson, M.] Skane Univ Hosp Lund, Lund, Sweden
dc.contributor.authoraffiliation[Fagioli, F.] Univ Turin, Regina Margherita Childrens Hosp, Paediat Oncohaematol Dept, Dept Publ Hlth & Pediat, Turin, Italy
dc.contributor.authoraffiliation[Fedenko, A.] PA Herzen Canc Res Inst, Moscow, Russia
dc.contributor.authoraffiliation[Ferraresi, V] IRCCS Regina Elena Natl Canc Inst, Sarcomas & Rare Tumors Unit, Rome, Italy
dc.contributor.authoraffiliation[Ferrari, A.] Fdn IRCCS Ist Nazl Tumori, Pediat Oncol Unit, Milan, Italy
dc.contributor.authoraffiliation[Gaspar, N.] Paris Saclay Univ, Gustave Roussy Canc Ctr, Dept Oncol Child & Adolescents, Villejuif, France
dc.contributor.authoraffiliation[Gasperoni, S.] Azienda Osped Univ Careggi, Dept Oncol & Robot Surg, Florence, Italy
dc.contributor.authoraffiliation[Gelderblom, H.] Leiden Univ Med Ctr, Dept Med Oncol, Leiden, Netherlands
dc.contributor.authoraffiliation[Gouin, F.] Ctr Leon Berard Lyon, Lyon, France
dc.contributor.authoraffiliation[Grignani, G.] FPO IRCCS, Candiolo Canc Inst, Candiolo, Italy
dc.contributor.authoraffiliation[Gronchi, A.] Fdn IRCCS Ist Nazl Tumori, Dept Surg, Milan, Italy
dc.contributor.authoraffiliation[Gronchi, A.] Univ Milan, Milan, Italy
dc.contributor.authoraffiliation[Haas, R.] Netherlands Canc Inst, Dept Radiotherapy, Leiden, Netherlands
dc.contributor.authoraffiliation[Haas, R.] Leiden Univ Med Ctr, Dept Radiotherapy, Leiden, Netherlands
dc.contributor.authoraffiliation[Hassan, A. B.] Oxford Univ Hosp NHS Fdn Trust, Oxford, England
dc.contributor.authoraffiliation[Hassan, A. B.] Univ Oxford, Oxford, England
dc.contributor.authoraffiliation[Hindi, N.] Univ Hosp, Fdn Jimenez Diaz, Dept Med Oncol, Adv Therapies Sarcoma Lab, Madrid, Spain
dc.contributor.authoraffiliation[Martin-Broto, J.] Univ Hosp, Fdn Jimenez Diaz, Dept Med Oncol, Adv Therapies Sarcoma Lab, Madrid, Spain
dc.contributor.authoraffiliation[Hohenberger, P.] Mannheim Univ Med Ctr, Mannheim, Germany
dc.contributor.authoraffiliation[Kasper, B.] Mannheim Univ Med Ctr, Mannheim, Germany
dc.contributor.authoraffiliation[Joensuu, H.] Helsinki Univ Hosp HUH, Helsinki, Finland
dc.contributor.authoraffiliation[Joensuu, H.] Univ Helsinki, Helsinki, Finland
dc.contributor.authoraffiliation[Jones, R. L.] Royal Marsden Hosp, Sarcoma Unit, London, England
dc.contributor.authoraffiliation[Jones, R. L.] Inst Canc Res, London, England
dc.contributor.authoraffiliation[Messiou, C.] Inst Canc Res, London, England
dc.contributor.authoraffiliation[Miah, A. B.] Inst Canc Res, London, England
dc.contributor.authoraffiliation[Jungels, C.] Univ Libre Bruxelles, Inst Jules Bordet, Med Oncol Clin, Brussels, Belgium
dc.contributor.authoraffiliation[Jutte, P.] Univ Med Ctr Groningen, Groningen, Netherlands
dc.contributor.authoraffiliation[Ladenstein, R.] Univ Med Ctr Groningen, Groningen, Netherlands
dc.contributor.authoraffiliation[Kager, L.] St Anna Childrens Hosp, Vienna, Austria
dc.contributor.authoraffiliation[Kager, L.] Childrens Canc Res Inst CCRI, Dept Pediat, Vienna, Austria
dc.contributor.authoraffiliation[Kager, L.] Med Univ Vienna, Childrens Canc Res Inst, Vienna, Austria
dc.contributor.authoraffiliation[Kawai, A.] Natl Canc Ctr, Dept Musculoskeletal Oncol, Tokyo, Japan
dc.contributor.authoraffiliation[Kopeckova, K.] Univ Hosp Motol, Prague, Czech Republic
dc.contributor.authoraffiliation[Krakorova, D. A.] Masaryk Mem Canc Inst, Brno, Czech Republic
dc.contributor.authoraffiliation[Le Cesne, A.] Gustave Roussy, Dept Canc Med, Villejuif, France
dc.contributor.authoraffiliation[Legius, E.] Katholieke Univ Leuven, Dept Human Genet, Univ Hosp Leuven, Leuven, Belgium
dc.contributor.authoraffiliation[Leithner, A.] Med Univ Graz, Dept Orthopaed & Trauma, Graz, Austria
dc.contributor.authoraffiliation[Scheipl, S.] Med Univ Graz, Dept Orthopaed & Trauma, Graz, Austria
dc.contributor.authoraffiliation[Pousa, A. Lopez] Hosp Univ Santa Creu & St Pau, Med Oncol Dept, Barcelona, Spain
dc.contributor.authoraffiliation[Merimsky, O.] Tel Aviv Sourasky Med Ctr Ichilov, Tel Aviv, Israel
dc.contributor.authoraffiliation[Messiou, C.] Royal Marsden Hosp, Dept Radiol, London, England
dc.contributor.authoraffiliation[Miah, A. B.] Royal Marsden Hosp, Dept Oncol, London, England
dc.contributor.authoraffiliation[Mir, O.] Gustave Roussy, Dept Ambulatory Canc Care, Villejuif, France
dc.contributor.authoraffiliation[Montemurro, M.] CHU Vaudois, Dept Oncol, Lausanne, Switzerland
dc.contributor.authoraffiliation[Morland, B.] Birmingham Womens & Childrens NHS Fdn Trust, Birmingham, W Midlands, England
dc.contributor.authoraffiliation[Morosi, C.] IRCCS Fdn Natl Canc Inst, Dept Radiol, Milan, Italy
dc.contributor.authoraffiliation[Palmerini, E.] IRCCS Ist Ortoped Rizzoli, Dept Osteoncol Bone & Soft Tissue Sarcomas & Inno, Bologna, Italy
dc.contributor.authoraffiliation[Pantaleo, M. A.] IRCCS Azienda Osped Univ Bologna, Div Oncol, Bologna, Italy
dc.contributor.authoraffiliation[Piana, R.] Univ Citta Salute & Sci Torino, Azienda Osped, Turin, Italy
dc.contributor.authoraffiliation[Piperno-Neumann, S.] Inst Curie, Dept Med Oncol, Paris, France
dc.contributor.authoraffiliation[Reichardt, P.] Helios Klinikum Berlin Buch, Berlin, Germany
dc.contributor.authoraffiliation[Rutkowski, P.] Maria Sklodowska Curie Natl Res Inst Oncol, Dept Soft Tissue Bone Sarcoma & Melanoma, Warsaw, Poland
dc.contributor.authoraffiliation[Safwat, A. A.] Aarhus Univ Hosp, Aarhus, Denmark
dc.contributor.authoraffiliation[Sangalli, C.] Fdn IRCCS Ist Nazl Tumori, Dept Radiotherapy, Milan, Italy
dc.contributor.authoraffiliation[Schoffski, P.] Univ Hosp Leuven, Leuven Canc Inst, Dept Gen Med Oncol, Leuven, Belgium
dc.contributor.authoraffiliation[Sleijfer, S.] Erasmus MC Canc Inst, Dept Med Oncol, Rotterdam, Netherlands
dc.contributor.authoraffiliation[van der Graaf, W. T. A.] Erasmus MC Canc Inst, Dept Med Oncol, Rotterdam, Netherlands
dc.contributor.authoraffiliation[Strauss, D.] Royal Marsden Hosp, Dept Surg, London, England
dc.contributor.authoraffiliation[Trama, A.] Fdn IRCCS Ist Nazl Tumori, Dept Res, Evaluat Epidemiol Unit, Milan, Italy
dc.contributor.authoraffiliation[Unk, M.] Inst Oncol Ljubljana, Ljubljana, Slovenia
dc.contributor.authoraffiliation[van de Sande, M. A. J.] Leiden Univ Med Ctr, Dept Orthoped Surg, Leiden, Netherlands
dc.contributor.authoraffiliation[van der Graaf, W. T. A.] Netherlands Canc Inst, Dept Med Oncol, Amsterdam, Netherlands
dc.contributor.authoraffiliation[van Houdt, W. J.] Netherlands Canc Inst, Dept Surg Oncol, Amsterdam, Netherlands
dc.contributor.authoraffiliation[Frebourg, T.] Normandie Univ, Dept Genet, Normandy Ctr Genom & Personalized Med, UNIROUEN,Inserm U1245, Rouen, France
dc.contributor.authoraffiliation[Casali, P. G.] Univ Milan, Dept Oncol & Hematooncol, Milan, Italy
dc.contributor.authoraffiliation[Strauss, S. J.] ESMO Guidelines Comm, ESMO Head Off, Via Ginevra 4, CH-6900 Lugano, Switzerland
dc.contributor.authoraffiliation[Le Grange, F.] ESMO Guidelines Comm, ESMO Head Off, Via Ginevra 4, CH-6900 Lugano, Switzerland
dc.contributor.authoraffiliation[ERN PaedCan] ESMO Guidelines Comm, ESMO Head Off, Via Ginevra 4, CH-6900 Lugano, Switzerland
dc.contributor.groupESMO Guidelines Comm
dc.contributor.groupEURACAN
dc.contributor.groupGENTURIS
dc.contributor.groupERN PaedCan
dc.date.accessioned2025-01-07T15:50:26Z
dc.date.available2025-01-07T15:50:26Z
dc.date.issued2021-11-20
dc.description.abstractPrimary bone sarcomas (BSs) account for <0.2% of malignant neoplasms across all ages.1 The overall incidence rate ranges between 0.8 and 0.9 cases per 100 000/year, with single BS types having no more than 0.3 incident cases per 100 000/year. Osteosarcoma and Ewing sarcoma (ES) have a relatively high incidence in the second decade of life, whereas conventional chondrosarcomas are more common in older age.2
dc.description.versionSi
dc.identifier.citationStrauss SJ, Frezza AM, Abecassis N, Bajpai J, Bauer S, Biagini R, et al. Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2021 Dec;32(12):1520-1536.
dc.identifier.doi10.1016/j.annonc.2021.08.1995
dc.identifier.essn1569-8041
dc.identifier.issn0923-7534
dc.identifier.unpaywallURLhttp://www.annalsofoncology.org/article/S0923753421042800/pdf
dc.identifier.urihttps://hdl.handle.net/10668/27443
dc.identifier.wosID721610600011
dc.issue.number12
dc.journal.titleAnnals of oncology
dc.journal.titleabbreviationAnn. oncol.
dc.language.isoen
dc.organizationInstituto de Investigación Biomédica de Sevilla (IBIS)
dc.organizationSAS - Hospital Universitario Virgen del Rocío
dc.page.number1520-1536
dc.publisherElsevier
dc.relation.publisherversionhttps://linkinghub.elsevier.com/retrieve/pii/S0923-7534(21)04280-0
dc.rights.accessRightsRestricted Access
dc.subjectbone sarcoma
dc.subjectclinical practice guideline
dc.subjectdiagnosis
dc.subjecttreatment
dc.subjectfollow-up
dc.subjectmanagement
dc.subjectLocalized ewing sarcoma
dc.subjectGiant-cell tumor
dc.subjectMalignant fibrous histiocytoma
dc.subjectHigh-grade osteosarcoma
dc.subjectHigh-dose ifosfamide
dc.subjectOpen-label
dc.subjectPhase-ii
dc.subjectNeoadjuvant chemotherapy
dc.subjectPrognostic-factors
dc.subjectMuramyl tripeptide
dc.subject.decsIncidencia
dc.subject.decsHuesos
dc.subject.decsSarcoma
dc.subject.decsSarcoma de Ewing
dc.subject.decsOsteosarcoma
dc.subject.decsVida
dc.subject.decsNeoplasias
dc.subject.decsCondrosarcoma
dc.subject.meshSarcoma, Ewing
dc.subject.meshIncidence
dc.subject.meshOsteosarcoma
dc.subject.meshChondrosarcoma
dc.titleBone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number32
dc.wostypeArticle

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