SARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group

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dc.contributor.authorLuis Pinana, Jose
dc.contributor.authorLopez-Corral, Lucia
dc.contributor.authorMartino, Rodrigo
dc.contributor.authorMontoro, Juan
dc.contributor.authorVazquez, Lourdes
dc.contributor.authorPerez, Ariadna
dc.contributor.authorMartin-Martin, Gabriel
dc.contributor.authorFacal-Malvar, Ana
dc.contributor.authorFerrer, Elena
dc.contributor.authorPascual, Maria-Jesus
dc.contributor.authorSanz-Linares, Gabriela
dc.contributor.authorGago, Beatriz
dc.contributor.authorSanchez-Salinas, Andres
dc.contributor.authorVillalon, Lucia
dc.contributor.authorConesa-Garcia, Venancio
dc.contributor.authorOlave, Maria T.
dc.contributor.authorLopez-Jimenez, Javier
dc.contributor.authorMarcos-Corrales, Sara
dc.contributor.authorGarcia-Blazquez, Marta
dc.contributor.authorGarcia-Gutierrez, Valentin
dc.contributor.authorAngel Hernandez-Rivas, Jose
dc.contributor.authorSaus, Ana
dc.contributor.authorEspigado, Ildefonso
dc.contributor.authorAlonso, Carmen
dc.contributor.authorHernani, Rafael
dc.contributor.authorSolano, Carlos
dc.contributor.authorFerrer-Lores, Blanca
dc.contributor.authorGuerreiro, Manuel
dc.contributor.authorRuiz-Garcia, Montserrat
dc.contributor.authorLuis Munoz-Bellido, Juan
dc.contributor.authorNavarro, David
dc.contributor.authorCedillo, Angel
dc.contributor.authorSureda, Anna
dc.contributor.authorInfect Complications Subcomm Spani
dc.contributor.authoraffiliation[Luis Pinana, Jose] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Perez, Ariadna] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Ferrer, Elena] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Saus, Ana] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Hernani, Rafael] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Solano, Carlos] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Ferrer-Lores, Blanca] Hosp Clin Univ Valencia, Hematol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Luis Pinana, Jose] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Perez, Ariadna] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Saus, Ana] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Hernani, Rafael] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Solano, Carlos] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Ferrer-Lores, Blanca] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Navarro, David] Univ Valencia, Inst Invest Sanitaria Hosp Clin, Fdn INCLIVA, Valencia, Spain
dc.contributor.authoraffiliation[Lopez-Corral, Lucia] Hosp Univ Salamanca, Hematol Div, Salamanca, Spain
dc.contributor.authoraffiliation[Vazquez, Lourdes] Hosp Univ Salamanca, Hematol Div, Salamanca, Spain
dc.contributor.authoraffiliation[Martin-Martin, Gabriel] Hosp Univ Salamanca, Hematol Div, Salamanca, Spain
dc.contributor.authoraffiliation[Marcos-Corrales, Sara] Hosp Univ Salamanca, Hematol Div, Salamanca, Spain
dc.contributor.authoraffiliation[Garcia-Blazquez, Marta] Hosp Univ Salamanca, Hematol Div, Salamanca, Spain
dc.contributor.authoraffiliation[Martino, Rodrigo] Hosp Santa Creu & Sant Pau, Hematol Div, Barcelona, Spain
dc.contributor.authoraffiliation[Montoro, Juan] Hosp Univ & Politecn La Fe, Hematol Div, Valencia, Spain
dc.contributor.authoraffiliation[Facal-Malvar, Ana] Hosp Univ & Politecn La Fe, Hematol Div, Valencia, Spain
dc.contributor.authoraffiliation[Guerreiro, Manuel] Hosp Univ & Politecn La Fe, Hematol Div, Valencia, Spain
dc.contributor.authoraffiliation[Pascual, Maria-Jesus] Hosp Reg Univ Carlos Haya, Hematol Div, Malaga, Spain
dc.contributor.authoraffiliation[Gago, Beatriz] Hosp Reg Univ Carlos Haya, Hematol Div, Malaga, Spain
dc.contributor.authoraffiliation[Sanz-Linares, Gabriela] Hosp Duran & Reynals, Hematol Div, Inst Catala Oncol, Barcelona, Spain
dc.contributor.authoraffiliation[Sureda, Anna] Hosp Duran & Reynals, Hematol Div, Inst Catala Oncol, Barcelona, Spain
dc.contributor.authoraffiliation[Sanchez-Salinas, Andres] Hosp Clin Univ Virgen de la Arrixaca, Hematol Div, Murcia, Spain
dc.contributor.authoraffiliation[Villalon, Lucia] Hosp Univ Fdn Alcorcon, Hematol Div, Madrid, Spain
dc.contributor.authoraffiliation[Conesa-Garcia, Venancio] Hosp Gen Univ Elx, Hematol Div, Elche, Spain
dc.contributor.authoraffiliation[Olave, Maria T.] Hosp Clin Univ Lozano Blesa, Hematol Div, IIS Aragon, Zaragoza, Spain
dc.contributor.authoraffiliation[Lopez-Jimenez, Javier] Hosp Ramon & Cajal, Hematol Div, Madrid, Spain
dc.contributor.authoraffiliation[Garcia-Gutierrez, Valentin] Hosp Ramon & Cajal, Hematol Div, Madrid, Spain
dc.contributor.authoraffiliation[Angel Hernandez-Rivas, Jose] Hosp Univ Infanta Leonor, Hematol Div, Madrid, Spain
dc.contributor.authoraffiliation[Espigado, Ildefonso] Univ Seville, Hosp Univ Virgen Macarena, Hematol Div, Hosp Univ Virgen del Rocio,IBiS,CSIC, Seville, Spain
dc.contributor.authoraffiliation[Alonso, Carmen] Hosp Arnau Vilanova, Hematol Div, Valencia, Spain
dc.contributor.authoraffiliation[Solano, Carlos] Univ Valencia, Sch Med, Dept Med, Valencia, Spain
dc.contributor.authoraffiliation[Ruiz-Garcia, Montserrat] Hosp Gen Univ Elx, Microbiol Dept, Elche, Spain
dc.contributor.authoraffiliation[Luis Munoz-Bellido, Juan] Hosp Univ Salamanca, Microbiol Dept, Salamanca, Spain
dc.contributor.authoraffiliation[Navarro, David] Hosp Clin Univ Valencia, Microbiol Dept, Valencia, Spain
dc.contributor.authoraffiliation[Cedillo, Angel] Hematopoiet Stem Cell Transplantat & Cell Therapy, Madrid, Spain
dc.contributor.funderVanderbilt Institute for Clinical and Translational Research
dc.contributor.funderSpanish Society of Hematology (SEHH)
dc.date.accessioned2025-01-07T12:14:12Z
dc.date.available2025-01-07T12:14:12Z
dc.date.issued2021-11-02
dc.description.abstractThis is a multicenter prospective observational study that included a large cohort (n = 397) of allogeneic (allo-HSCT; (n = 311) and autologous (ASCT) hematopoietic stem cell transplant (n = 86) recipients who were monitored for antibody detection within 3-6 weeks after complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination from February 1, 2021, to July 20, 2021. Most patients (n = 387, 97.4%) received mRNA-based vaccines. Most of the recipients (93%) were vaccinated more than 1 year after transplant. Detectable SARS-CoV-2-reactive antibodies were observed in 242 (78%) of allo-HSCT and in 73 (85%) of ASCT recipients. Multivariate analysis in allo-HSCT recipients identified lymphopenia
dc.identifier.doi10.1002/ajh.26385
dc.identifier.essn1096-8652
dc.identifier.issn0361-8609
dc.identifier.pmid34695229
dc.identifier.unpaywallURLhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26385
dc.identifier.urihttps://hdl.handle.net/10668/24349
dc.identifier.wosID713672100001
dc.issue.number1
dc.journal.titleAmerican journal of hematology
dc.journal.titleabbreviationAm. j. hematol.
dc.language.isoen
dc.organizationSAS - Hospital Universitario Regional de Málaga
dc.page.number30-42
dc.publisherWiley
dc.rights.accessRightsopen access
dc.subjectChronic lymphocytic-leukemia
dc.subjectClinical characteristics
dc.subjectInfluenza vaccination
dc.subjectInfections
dc.subjectImmunogenicity
dc.subjectMalignancies
dc.subjectAdults
dc.titleSARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number97
dc.wostypeArticle

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