Hypersensitivity Reactions to Cancer Chemotherapy: Practical Recommendations of ARADyAL for Diagnosis and Desensitization

Simple item page
dc.contributor.authorVega, A.
dc.contributor.authorJimenez-Rodriguez, T-W
dc.contributor.authorBarranco, R.
dc.contributor.authorBartra, J.
dc.contributor.authorDieguez, M. C.
dc.contributor.authorDona, I
dc.contributor.authorFernandez-Rivas, M.
dc.contributor.authorGandolfo-Cano, M.
dc.contributor.authorGastaminza-Lasarte, G.
dc.contributor.authorGonzalez-Mancebo, E.
dc.contributor.authorCaballer, B. de la Hoz
dc.contributor.authorSanchez-Morillas, L.
dc.contributor.authorTorres, M. J.
dc.contributor.authorBerges-Gimeno, M. P.
dc.contributor.authorMunoz-Cano, R.
dc.contributor.authoraffiliation[Vega, A.] Hosp Univ Guadalajara, Dept Allergy, Guadalajara, Spain
dc.contributor.authoraffiliation[Vega, A.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Jimenez-Rodriguez, T-W] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Barranco, R.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Bartra, J.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Dieguez, M. C.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Dona, I] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Fernandez-Rivas, M.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Gandolfo-Cano, M.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Gastaminza-Lasarte, G.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Gonzalez-Mancebo, E.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Caballer, B. de la Hoz] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Sanchez-Morillas, L.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Torres, M. J.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Berges-Gimeno, M. P.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Munoz-Cano, R.] Inst Salud Carlos III ISCIII, ARADyAL Spanish Network RD16 0006, Fdn Espanola Ciencia & Tecnol FECyT, Madrid, Spain
dc.contributor.authoraffiliation[Vega, A.] Univ Int Catalunya, Fac Med, Barcelona, Spain
dc.contributor.authoraffiliation[Jimenez-Rodriguez, T-W] Alicante Gen Univ Hosp ISABIAL, Allergy Sect, Alicante, Spain
dc.contributor.authoraffiliation[Barranco, R.] Hosp Univ 12 Octubre & I 12, Dept Allergy, Madrid, Spain
dc.contributor.authoraffiliation[Dieguez, M. C.] Hosp Univ 12 Octubre & I 12, Dept Allergy, Madrid, Spain
dc.contributor.authoraffiliation[Bartra, J.] Univ Barcelona, Hosp Clin, Allergy Sect, Pneumol Dept,IRCE Inst Invest Biomed August Pi &, Barcelona, Spain
dc.contributor.authoraffiliation[Munoz-Cano, R.] Univ Barcelona, Hosp Clin, Allergy Sect, Pneumol Dept,IRCE Inst Invest Biomed August Pi &, Barcelona, Spain
dc.contributor.authoraffiliation[Dona, I] Hosp Civil, Inst Invest Biomed Malaga IBIMA, Allergy Res Grp, Malaga, Spain
dc.contributor.authoraffiliation[Torres, M. J.] Hosp Civil, Inst Invest Biomed Malaga IBIMA, Allergy Res Grp, Malaga, Spain
dc.contributor.authoraffiliation[Dona, I] Hosp Civil, Hosp Reg Univ Malaga, Allergy Unit, Malaga, Spain
dc.contributor.authoraffiliation[Torres, M. J.] Hosp Civil, Hosp Reg Univ Malaga, Allergy Unit, Malaga, Spain
dc.contributor.authoraffiliation[Fernandez-Rivas, M.] UCM, Hosp Clin San Carlos, Serv Alergia, IdISSC, Madrid, Spain
dc.contributor.authoraffiliation[Sanchez-Morillas, L.] UCM, Hosp Clin San Carlos, Serv Alergia, IdISSC, Madrid, Spain
dc.contributor.authoraffiliation[Gandolfo-Cano, M.] Hosp Univ Fuenlabrada, Allergy Dept, Fuenlabrada, Spain
dc.contributor.authoraffiliation[Gonzalez-Mancebo, E.] Hosp Univ Fuenlabrada, Allergy Dept, Fuenlabrada, Spain
dc.contributor.authoraffiliation[Gandolfo-Cano, M.] IdiPAZ, Madrid, Spain
dc.contributor.authoraffiliation[Gonzalez-Mancebo, E.] IdiPAZ, Madrid, Spain
dc.contributor.authoraffiliation[Gastaminza-Lasarte, G.] Clin Univ Navarra, Allergy Dept, Pamplona, Spain
dc.contributor.authoraffiliation[Caballer, B. de la Hoz] Ramon y Cajal Univ Hosp, Allergy Dept, Madrid, Spain
dc.contributor.authoraffiliation[Berges-Gimeno, M. P.] Ramon y Cajal Univ Hosp, Allergy Dept, Madrid, Spain
dc.contributor.authoraffiliation[Caballer, B. de la Hoz] IRYCIS, Madrid, Spain
dc.contributor.authoraffiliation[Berges-Gimeno, M. P.] IRYCIS, Madrid, Spain
dc.contributor.authoraffiliation[Caballer, B. de la Hoz] Univ Alcala, Madrid, Spain
dc.contributor.funderInstituto de Salud Carlos III (ISCIII)
dc.contributor.funderFondo Europeo de Desarrollo Regional -FEDER
dc.date.accessioned2025-01-07T12:19:58Z
dc.date.available2025-01-07T12:19:58Z
dc.date.issued2021-01-01
dc.description.abstractRapid drug desensitization has enabled first-line therapies in patients with drug hypersensitivity reactions to chemotherapeutic drugs including monoclonal antibodies. Desensitization is a safe and highly effective procedure, not only for IgE-mediated reactions, but also for those mediated by non-IgE mechanisms. The likelihood of breakthrough reactions during desensitization is low, and most are mild; in fact, moderate-to-severe reactions are infrequent. In this document, 16 allergy departments belonging to the Spanish research network ARADyAL present a review of the available scientific evidence and provide general guidelines for the diagnosis and management of drug hypersensitivity reactions to chemotherapeutic drugs and monoclonal antibodies. Emphasis is placed on the desensitization procedure.
dc.identifier.doi10.18176/jiaci.0712
dc.identifier.essn1698-0808
dc.identifier.issn1018-9068
dc.identifier.pmid34045179
dc.identifier.unpaywallURLhttp://www.jiaci.org/revistas/vol31issue5_1.pdf
dc.identifier.urihttps://hdl.handle.net/10668/24474
dc.identifier.wosID724949000002
dc.issue.number5
dc.journal.titleJournal of investigational allergology and clinical immunology
dc.journal.titleabbreviationJ. invest. allergol. clin. immunol.
dc.language.isoen
dc.organizationSAS - Hospital Universitario Regional de Málaga
dc.organizationInstituto de Investigación Biomédica de Málaga - Plataforma Bionand (IBIMA)
dc.page.number364-384
dc.publisherEsmon publicidad s a, dept allergy & clin immunol, clin univ navarra
dc.rights.accessRightsopen access
dc.subjectDrug allergy
dc.subjectDrug hypersensitivity
dc.subjectDesensitization
dc.subjectChemotherapy
dc.subjectDrug challenge
dc.subjectMonoclonal antibodies
dc.subjectSuccessful oral desensitization
dc.subjectHereditary alpha-tryptasemia
dc.subjectRapid drug desensitization
dc.subjectBasophil activation test
dc.subjectStevens-johnson-syndrome
dc.subjectMonoclonal-antibodies
dc.subjectIge desensitization
dc.subjectSkin-test
dc.subjectCarboplatin hypersensitivity
dc.subjectGeneral-considerations
dc.titleHypersensitivity Reactions to Cancer Chemotherapy: Practical Recommendations of ARADyAL for Diagnosis and Desensitization
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number31
dc.wostypeArticle

Files

Collections

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS)
Instituto de Investigación Biomédica de Málaga - Plataforma Bionand (IBIMA)

© 2023 – Repositorio Institucional de Salud de Andalucía - Fundación Pública Andaluza Progreso y Salud - Consejería de Salud y Consumo de la Junta de Andalucía