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Virological Failure in HIV to Triple Therapy With Dolutegravir-Based Firstline Treatment: Rare but Possible.

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PMC6324549.pdf (176.2 KB)
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URI: http://hdl.handle.net/10668/13411
DOI: 10.1093/ofid/ofy332
Date
2018-12-10
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Abstract
We describe a case of virological failure during initial treatment with tenofovir disoproxil fumarate/emtricitabine/dolutegravir twice daily, with concomitant rifampin treatment of staphylococcal infection, selection of R263K + E157Q, and low plasma dolutegravir levels. Using rifampin together with dolutegravir may require closer follow-up, and, if possible, plasma dolutegravir levels should be monitored.
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dolutegravir, failure, firstline
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http://hdl.handle.net/10668/13411
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SAS - Hospital Universitario San Cecilio