Publication: Gender Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication.
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2018-09-15
Authors
Manfredini, Roberto
Lamberti, Nicola
Manfredini, Fabio
Straudi, Sofia
Fabbian, Fabio
Rodriguez Borrego, Maria Aurora
Basaglia, Nino
Carmona Torres, Juan Manuel
Lopez Soto, Pablo Jesus
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Abstract
Background: Peripheral artery disease (PAD) is a common cardiovascular pathology that affects mobility. In previous research, supervised exercise, a recommended treatment for claudication, was less effective in women. This study retrospectively investigated whether functional outcomes exhibit sex differences following a pain-free, home-based exercise program for PAD patients. Materials and Methods: Patients with PAD and claudication enrolled to a structured home-based program from 2003 to 2016 were studied. The program was prescribed at the hospital and based on two daily 10-minute pain-free walking sessions at progressively increasing speed. Outcome measures, which were assessed at baseline and discharge, were pain threshold speed (PTS) and maximal (Smax) during a treadmill test and pain-free walking distance (PFWD) and total distance walked in 6 minutes (6MWD). The ankle-brachial index (ABI), program duration, and patient adherence were determined. Results: A total of 1007 patients (women; nā=ā264; 26%) were enrolled. At baseline, compared to men, women exhibited similar ABI values but lower PTS and PFWD values (pā
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exercise therapy, gender, peripheral artery disease, rehabilitation, women