Publication: Prevalencia de hepatitis C en pacientes con trastornos psicóticos no afectivos
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2020-07
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Sociedad Española de Patología Digestiva (SEPD) y Arán Ediciones, S.L.
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Abstract
Introducción: nuestro objetivo fue determinar la prevalencia de infección por virus de la hepatitis C (VHC) en pacientes con trastornos psicóticos no afectivos y compararla con los datos poblacionales. Material y métodos: se realizó un estudio observacional mediante la determinación de anti-VHC (RNA-VHC en los seropositivos) sobre 425 muestras séricas de pacientes con psicosis no afectiva. Resultados: ocho pacientes presentaron anti-VHC positivo (1,9 %) y cinco, RNA-VHC detectable (1,2 %). La prevalencia de viremia fue significativamente mayor que la de la población general (OR 5,4; IC 95 %: 1,9-14,6). Conclusiones: los pacientes con trastorno psicótico no afectivo presentan una prevalencia de infección activa superior a la población general y deberían ser objeto de un cribado sistemático.
Introduction: the goal of this study was to determine the prevalence of hepatitis C virus (HCV) infection in patients with non-affective psychotic disorders and to compare it with population-based data. Material and methods: an observational study was performed that measured anti-HCV antibodies (HCV-RNA in case of seropositivity) in 425 serum samples from patients with non-affective psychosis. Eight patients were positive for anti-HCV (1.9 %) and five had detectable HCV-RNA (1.2 %). The prevalence of viremia was significantly higher than in the general population (OR: 5.4; 95 % CI: 1.9-14.6). Conclusions: patients with non-affective psychotic disorder have a higher prevalence of active infection than that of the general population and should undergo systematic screening.
Introduction: the goal of this study was to determine the prevalence of hepatitis C virus (HCV) infection in patients with non-affective psychotic disorders and to compare it with population-based data. Material and methods: an observational study was performed that measured anti-HCV antibodies (HCV-RNA in case of seropositivity) in 425 serum samples from patients with non-affective psychosis. Eight patients were positive for anti-HCV (1.9 %) and five had detectable HCV-RNA (1.2 %). The prevalence of viremia was significantly higher than in the general population (OR: 5.4; 95 % CI: 1.9-14.6). Conclusions: patients with non-affective psychotic disorder have a higher prevalence of active infection than that of the general population and should undergo systematic screening.
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MeSH Terms
Medical Subject Headings::Organisms::Viruses::Hepatitis Viruses::Hepacivirus
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Viral::Hepatitis Antibodies::Hepatitis C Antibodies
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
Medical Subject Headings::Diseases::Virus Diseases::Hepatitis, Viral, Human::Hepatitis C
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Psychotic Disorders
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Viral::Hepatitis Antibodies::Hepatitis C Antibodies
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
Medical Subject Headings::Diseases::Virus Diseases::Hepatitis, Viral, Human::Hepatitis C
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Psychotic Disorders
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders
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Keywords
Hepatitis C, Prevalencia, Trastorno mental grave, Trastorno psicótico no afectivo, Prevalence, Severe mental disorders, Non-affective psychotic disorder
Citation
Cuadrado A, Cabezas J, Llerena S, Nieves Salceda JF, Fortea JI, Crespo-Facorro B, et al. Prevalencia de hepatitis C en pacientes con trastornos psicóticos no afectivos. Rev Esp Enferm Dig. 2020 Jul;112(7):550-554.