Influence of renal function on anticoagulation control in patients with non-valvular atrial fibrillation taking vitamin K antagonists

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Background and PurposeChronic kidney disease (CKD) has been related to poor anticoagulation control and an increased risk of bleeding. This study aims to evaluate the association between impaired renal function (eGFR 2 points) showed no significant predictive capacity for TTR (AUC 0.528, P=.354). The average TTR was similar for both sexes (P=.255), but with a higher percentage of males subjects with TTR 65% (P=.013).ConclusionChronic kidney disease is associated with poor anticoagulation control in patients with non-valvular AF taking VKA. The SAMe-TT2R2 score was not predictive of poor TTR in the subgroup with CKD, although a modest predictive value for poor TTR was found in those without CKD.
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anticoagulation, atrial fibrillation, chronic kidney disease, vitamin K antagonist, Chronic kidney-disease, Same-tt2r2 score, Stroke, Quality, Warfarin, Risk, Mortality, Spain, Care, Inr