Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/726
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dc.contributor.authorFagundo, Ana B-
dc.contributor.authorTorre, Rafael de la-
dc.contributor.authorJiménez-Murcia, Susana-
dc.contributor.authorAgüera, Zaida-
dc.contributor.authorGranero, Roser-
dc.contributor.authorTárrega, Salomé-
dc.contributor.authorBotella, Cristina-
dc.contributor.authorBaños, Rosa-
dc.contributor.authorFernández-Real, Jose M-
dc.contributor.authorRodríguez, Roser-
dc.contributor.authorForcano, Laura-
dc.contributor.authorFrühbeck, Gema-
dc.contributor.authorGómez-Ambrosi, Javier-
dc.contributor.authorTinahones Madueño, Francisco José-
dc.contributor.authorFernández-García, Jose Carlos-
dc.contributor.authorCasanueva, Felipe F-
dc.contributor.authorFernández-Aranda, Fernando-
dc.date.accessioned2013-01-08T10:33:37Z-
dc.date.available2013-01-08T10:33:37Z-
dc.date.issued2012-08-
dc.identifier.citationFagundo AB, de la Torre R, Jiménez-Murcia S, Agüera Z, Granero R, Tárrega S, et al. Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity. PLoS ONE. 2012; 7(8):e43382es
dc.identifier.issn1932-6203 (Online)-
dc.identifier.urihttp://hdl.handle.net/10668/726-
dc.descriptionJournal Article; Research Support, Non-U.S. Gov't;es
dc.description.abstractBACKGROUND Extreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN), obese subjects (OB) and healthy eating/weight controls (HC). METHODS Thirty five AN patients, fifty two OB and one hundred thirty seven HC were compared using the Wisconsin Card Sorting Test (WCST); Stroop Color and Word Test (SCWT); and Iowa Gambling Task (IGT). All participants were female, aged between 18 and 60 years. RESULTS There was a significant difference in IGT score (F(1.79); p<.001), with AN and OB groups showing the poorest performance compared to HC. On the WCST, AN and OB made significantly more errors than controls (F(25.73); p<.001), and had significantly fewer correct responses (F(2.71); p<.001). Post hoc analysis revealed that the two clinical groups were not significantly different from each other. Finally, OB showed a significant reduced performance in the inhibition response measured with the Stroop test (F(5.11); p<.001) compared with both AN and HC. CONCLUSIONS These findings suggest that EWC subjects (namely AN and OB) have similar dysfunctional executive profile that may play a role in the development and maintenance of such disorders.es
dc.description.sponsorshipFinancial support was received from Fondo de Investigación Sanitaria -FIS (PI081714; PI11/210) and AGAUR (2009SGR1554, 2009SGR718);es
dc.description.sponsorshipMinisterio de Ciencia e Innovación Subprograma Juan de la Cierva (JCI-2011-09248);es
dc.description.sponsorshipCIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) and CIBER Salud Mental (CIBERsam), are an initiative of ISCIII.es
dc.language.isoenes
dc.publisherPublic Library of Sciencees
dc.relation.ispartofPloS onees
dc.subjectAnorexia Nerviosaes
dc.subjectTrastorno por Déficit de Atención con Hiperactividades
dc.subjectObesidades
dc.subjectPruebas Neuropsicológicases
dc.subjectToma de Concienciaes
dc.subjectImagen Corporales
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Mental Disorders::Eating Disorders::Anorexia Nervosaes
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Attention Deficit and Disruptive Behavior Disorders::Attention Deficit Disorder with Hyperactivityes
dc.subject.meshMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesityes
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Testses
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition::Awarenesses
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Imagees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.titleExecutive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity.es
dc.typeinfo:eu-repo/semantics/articlees
dc.description.versionYeses
dc.identifier.pmid22927962-
dc.rights.accessRightsAcceso abiertoes
dc.identifier.doi10.1371/journal.pone.0043382-
dc.type.versioninfo:eu-repo/semantics/publishedes
dc.relation.publisherversionhttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043382es
dc.contributor.authoraffiliation[Fagundo,AB; Fernández-Aranda,F] Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain. [de la Torre,R; Jiménez-Murcia,S; Agüera,Z; Granero,R; Tárrega,S; Botella,C; Baños,R; Fernández-Real,JM; Rodríguez,R; Forcano,L; Frühbeck,G; Gómez-Ambrosi,J; Tinahones Madueño,FJ; Fernández-García,JC; Casanueva,FF; Fernández-Aranda,F] CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Spain. [de la Torre,R] Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM-Hospital del Mar Research Institute, Parc de Salut Mar, Barcelona, Spain. [Jiménez-Murcia,S; Fernández Aranda,F] Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain. [Granero,R; Tárrega,S] Laboratori d’Estadística Aplicada, Departament de Psicobiologia i Metodologia, Universitat Autònoma de Barcelona, Spain. [Botella,C] Department of Basic Psychology, Clinic and Psychobiology, University Jaume I, Castellón, Spain. [Baños,R] Department of Pyschological, Personality, Evaluation and Treatment, University of Valencia, Spain. [Fernández-Real,JM; Rodríguez,R] Service of Diabetes, Endocrinology and Nutrition, Institut d’Investigació Biomèdica de Girona (IdlBGi) Hospital Dr Josep Trueta, Girona, Spain. [Frühbeck,G; Gómez-Ambrosi,J] Department of Endocrinology, University of Navarra, Pamplona, Spain. [Tinahones Madueño,FJ; Fernández García,JC] Service of Diabetes, Endocrinology and Nutrition, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Casanueva,F] Endocrine Division, Complejo Hospitalario U. de Santiago, Santiago de Compostela University, Spain.es
dc.type.subtypeArtículoes
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