Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/3853
Title: Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis
Authors: Rivera-Izquierdo, Mario
Martínez-Ruiz, Virginia
Castillo-Ruiz, Elena Mercedes
Manzaneda-Navío, Miriam
Pérez-Gómez, Beatriz
Jiménez-Moleón, José Juan
metadata.dc.contributor.authoraffiliation: [Rivera-Izquierdo,M; Martínez-Ruiz,V; Castillo-Ruiz,EM; Manzaneda-Navío,M; Jiménez-Moleón,JJ] Department of Preventive Medicine and Public Health, School of Medicine, University of Granada, Granada, Spain. [Rivera-Izquierdo,M] Service of Preventive Medicine and Public Health, Hospital Clínico San Cecilio, Granada, Spain. [Martínez-Ruiz,V; Pérez-Gómez,B; Jiménez-Moleón,JJ] Centros de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. [Martínez-Ruiz,V; Jiménez-Moleón,JJ] Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA),Granada, Spain. [Pérez-Gómez,B] Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain.
Keywords: Occupational health;Night work;Rotating shift work;Circadian disruption;Heterogeneity analysis;Prostate cancer;Salud laboral;Horario de trabajo por turnos;Neoplasias de la próstata;Revisión sistemática;Metaanálisis
metadata.dc.subject.mesh: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Diseases::Male Urogenital Diseases::Genital Diseases, Male::Genital Neoplasms, Male::Prostatic Neoplasms
Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Human Activities::Work::Work Schedule Tolerance
Issue Date: 19-Feb-2020
Publisher: MDPI
Citation: Rivera-Izquierdo M, Martínez-Ruiz V, Castillo-Ruiz EM, Manzaneda-Navío M, Pérez-Gómez B, Jiménez-Moleón JJ. Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2020 Feb 19;17(4):1345
Abstract: The International Agency of Research in Cancer (IARC) has recently confirmed shift work as a type 2A carcinogen. The results presented in published epidemiological studies regarding prostate cancer are inconsistent and the association remains controversial. The aims of this study were: (a) to investigate the possible association between shift work and prostate cancer incidence, identifying possible sources of heterogeneity; and (b) to analyze the potential effect of publication bias. A search for cohort and case-control studies published from January 1980 to November 2019 was conducted. The quality of the articles was assessed using the Newcastle-Ottawa Scale. Pooled OR were calculated using random-effects models. Heterogeneity was evaluated using Cochran's Q test and data were stratified by potential sources of heterogeneity. Publication bias was analyzed. Eighteen studies were included. No association was found between rotating/night-shift work and prostate cancer, pooled OR 1.07 (95%CI 0.99 to 1.15), I2 = 45.7%, p = 0.016. Heterogeneity was eliminated when only cohort studies (pooled OR 1.03; 95%CI 0.96 to 1.10; I2 = 18.9%, p = 0.264) or high-quality studies (pooled OR 0.99; 95%CI 0.89 to 1.08; I2 = 0.0%, p = 0.571) were considered. A publication bias was detected. An association between shift work and prostate cancer cannot be confirmed with the available current data. Future analytical studies assessing more objective homogeneous exposure variables still seem necessary.
URI: http://hdl.handle.net/10668/3853
metadata.dc.relation.publisherversion: https://www.mdpi.com/1660-4601/17/4/1345/htm
metadata.dc.identifier.doi: 10.3390/ijerph17041345
ISSN: 1661-7827 (Print)
1660-4601 (Online)
Appears in Collections:01- Artículos - Hospital San Cecilio

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