Publication: Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia.
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Date
2022-07-16
Authors
Sanz-Canovas, Jaime
Lopez-Sampalo, Almudena
Cobos-Palacios, Lidia
Ricci, Michele
Hernandez-Negrin, Halbert
Mancebo-Sevilla, Juan Jose
Alvarez-Recio, Elena
Lopez-Carmona, Maria Dolores
Perez-Belmonte, Luis Miguel
Gómez-Huelgas, Ricardo
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MDPI
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Abstract
The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM.
Description
MeSH Terms
Aged
Aging
Diabetes Mellitus, Type 2
Frail Elderly
Frailty
Humans
Sarcopenia
Aging
Diabetes Mellitus, Type 2
Frail Elderly
Frailty
Humans
Sarcopenia
DeCS Terms
Fragilidad
Resistencia a la insulina
Enfermedades mitocondriales
Diabetes Mellitus tipo 2
Envejecimiento
Resistencia a la insulina
Enfermedades mitocondriales
Diabetes Mellitus tipo 2
Envejecimiento
CIE Terms
Keywords
Elderly, Frailty, Sarcopenia, Type 2 diabetes mellitus
Citation
Sanz-Cánovas J, López-Sampalo A, Cobos-Palacios L, Ricci M, Hernández-Negrín H, Mancebo-Sevilla JJ, et al. Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia. Int J Environ Res Public Health. 2022 Jul 16;19(14):8677