Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/13149
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dc.contributor.authorDíaz-Caneja, Covadonga M
dc.contributor.authorCervilla, Jorge A
dc.contributor.authorHaro, Josep M
dc.contributor.authorArango, Celso
dc.contributor.authorde Portugal, Enrique
dc.date.accessioned2023-01-25T10:24:01Z-
dc.date.available2023-01-25T10:24:01Z-
dc.date.issued2018-10-30
dc.identifier.urihttp://hdl.handle.net/10668/13149-
dc.description.abstractEven if neurocognition is known to affect functional outcomes in schizophrenia, no previous study has explored the impact of cognition on functionality in delusional disorder (DD). We aimed to assess the effect of clinical characteristics, symptom dimensions and neuropsychological performance on psychosocial functioning and self-perceived functional impairment in DD. Seventy-five patients with a SCID-I confirmed diagnosis of DD underwent neurocognitive testing using a neuropsychological battery examining verbal memory, attention, working memory and executive functions. We assessed psychotic symptoms with the Positive and Negative Syndrome Scale, and calculated factor scores for four clinical dimensions: Paranoid, Cognitive, Affective and Schizoid. We conducted hierarchical linear regression models to identify predictors of psychosocial functioning, as measured with the Global Assessment of Functioning scale, and self-perceived functional impairment, as measured with the Sheehan's Disability Inventory. In the final linear regression models, higher scores in the Paranoid (β= 0.471, p  Impaired verbal memory and cognitive symptoms seem to affect functionality in DD, above and beyond the severity of the paranoid idea. This suggests a potential role for cognitive interventions in the management of DD.
dc.language.isoen
dc.subjectFunctional outcome
dc.subjectNeurocognition
dc.subjectNeuropsychology
dc.subjectParanoia
dc.subjectPsychosis
dc.subjectPsychosocial functioning
dc.subject.meshAdult
dc.subject.meshAttention
dc.subject.meshCognition
dc.subject.meshCognitive Behavioral Therapy
dc.subject.meshDisability Evaluation
dc.subject.meshExecutive Function
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMemory
dc.subject.meshMiddle Aged
dc.subject.meshNeuropsychological Tests
dc.subject.meshParanoid Disorders
dc.subject.meshPsychotic Disorders
dc.subject.meshSchizophrenia, Paranoid
dc.subject.meshSelf-Assessment
dc.subject.meshSocial Skills
dc.titleCognition and functionality in delusional disorder.
dc.typeresearch article
dc.identifier.pmid30388425
dc.rights.accessRightsopen access
dc.identifier.doi10.1016/j.eurpsy.2018.09.010
dc.identifier.essn1778-3585
dc.identifier.unpaywallURLhttps://www.cambridge.org/core/services/aop-cambridge-core/content/view/F43F6354253D6043A9FC4A9EB740E1C8/S0924933800008968a.pdf/div-class-title-cognition-and-functionality-in-delusional-disorder-div.pdf
dc.journal.titleEuropean psychiatry : the journal of the Association of European Psychiatrists
dc.journal.titleabbreviationEur Psychiatry
dc.organizationHospital Universitario San Cecilio
dc.organizationHospital Universitario San Cecilio
dc.page.number52-60
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.volume.number55
dc.type.hasVersionVoR
Appears in Collections:SAS - Hospital Universitario San Cecilio

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