Publication: Targeting gut microbiome, is it always a therapeutic option?
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Identifiers
Date
2020-11-09
Authors
Rodríguez-Nogales, Alba
Gálvez, Julio
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
The Lancet Publishing Group
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Abstract
Obstructive sleep apnea (OSA) is a common respiratory disorder associated with cardiovascular comorbidities and cancer due to chronic intermittent hypoxia (CIH). This condition affects the gut microbiome, altering its diversity and increasing intestinal permeability, which contributes to insulin resistance. Dysbiosis is linked to chronic diseases such as metabolic syndrome and cardiovascular disorders.
Description
MeSH Terms
Animals
Disease Management
Disease Susceptibility
Gastrointestinal Microbiome
Humans
Precision Medicine
Disease Management
Disease Susceptibility
Gastrointestinal Microbiome
Humans
Precision Medicine
DeCS Terms
Apnea obstructiva del sueño (AOS)
Hipoxia intermitente crónica (HIC)
Disbiosis del microbioma intestinal
Sistema nervioso simpático
Enfermedades cardiovasculares y comorbilidades
Hipoxia intermitente crónica (HIC)
Disbiosis del microbioma intestinal
Sistema nervioso simpático
Enfermedades cardiovasculares y comorbilidades
CIE Terms
Keywords
Obstructive sleep apnea (OSA), Chronic intermittent hypoxia (CIH), Gut microbiome, Oxidative stress, Insulin resistance
Citation
Rodríguez-Nogales A, Gálvez J. Targeting gut microbiome, is it always a therapeutic option? EBioMedicine. 2020 Dec;62:103099. doi: 10.1016/j.ebiom.2020.103099.