Publication:
Switch to subcutaneous infliximab during the SARS-CoV-2 pandemic: preliminary results.

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2022

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Argüelles-Arias, Federico
Fernández Álvarez, Paula
Castro Laria, Luisa
Maldonado Pérez, Belén
Belvis Jiménez, María
Merino-Bohórquez, Vicente
Caunedo Álvarez, Ángel
Calleja Hernández, Miguel Ángel

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Abstract

A new subcutaneous formulation of the infliximab biosimilar CT-P13 has recently been developed for the treatment of inflammatory bowel disease (IBD), providing response rates similar to intravenous treatment. The use of this new formulation was requested, in an effort to limit patient attendance at intravenous infusion centers and to maintain biological treatment during the COVID-19 pandemic. The objective of this observational, retrospective and descriptive study was to assess CT-P13 efficacy and safety after switching from intravenous to a subcutaneous formulation in patients with IBD receiving maintenance therapy. This article shows preliminary results after six months of follow-up.

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Biosimilar Pharmaceuticals
COVID-19
Drug Substitution
Gastrointestinal Agents
Humans
Inflammatory Bowel Diseases
Infliximab
Pandemics
Prospective Studies
Retrospective Studies
SARS-CoV-2
Treatment Outcome

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