Publication: Ovarian cancer risk factors by tumor aggressiveness: An analysis from the Ovarian Cancer Cohort Consortium.
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2019-01-14
Authors
Fortner, Renée T
Poole, Elizabeth M
Wentzensen, Nicolas A
Trabert, Britton
White, Emily
Arslan, Alan A
Patel, Alpa V
Setiawan, V Wendy
Visvanathan, Kala
Weiderpass, Elisabete
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Abstract
Ovarian cancer risk factors differ by histotype; however, within subtype, there is substantial variability in outcomes. We hypothesized that risk factor profiles may influence tumor aggressiveness, defined by time between diagnosis and death, independent of histology. Among 1.3 million women from 21 prospective cohorts, 4,584 invasive epithelial ovarian cancers were identified and classified as highly aggressive (death in
Description
MeSH Terms
Aged
Body Mass Index
Carcinoma, Ovarian Epithelial
Cohort Studies
Female
Humans
Middle Aged
Neoplasm Invasiveness
Ovarian Neoplasms
Parity
Pregnancy
Proportional Hazards Models
Prospective Studies
Risk Factors
Smoking
Body Mass Index
Carcinoma, Ovarian Epithelial
Cohort Studies
Female
Humans
Middle Aged
Neoplasm Invasiveness
Ovarian Neoplasms
Parity
Pregnancy
Proportional Hazards Models
Prospective Studies
Risk Factors
Smoking
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Keywords
aggressiveness, ovarian cancer, prospective cohort, risk factors, subtypes