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Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study.

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dc.contributor.authorSilva, Kátia Regina Penha da
dc.contributor.authorPapais Alvarenga, Regina Maria
dc.contributor.authorFernandez Y Fernandez, Oscar
dc.contributor.authorAlvarenga, Hélcio
dc.contributor.authorSantos Thuler, Luiz Claudio
dc.contributor.authoraffiliation[Penha da Silva, KR; Papais Alvarenga,RM] Neurology Department, Hospital da Lagoa, Federal University of the State of Rio de Janeiro(UNIRIO)Rio de Janeiro RJ,Brazil. [Penha da Silva, KR; Papais Alvarenga,RM; Alvarenga,H; Santos Thuler, LC] Postgraduate Master Program in Neurology, Federal University of the State of Rio de Janeiro(UNIRIO) Rio de Janeiro RJ,Brazil. [Fernandez y Fernandez,O] Neurology Department, Carlos Haya Teaching Hospital, Malaga, Spain.es
dc.date.accessioned2012-09-10T08:20:47Z
dc.date.available2012-09-10T08:20:47Z
dc.date.issued2009-06
dc.description.abstract[Port]Resumo – Objetivo: Avaliar os potenciais fatores de risco para o desenvolvimento de esclerose múltipla em pacientes brasileiros. Método: Um estudo caso-controle incluiu 81 pacientes atendidos no Departamento de Neurologia do Hospital da Lagoa, no Rio de Janeiro, e 81 controles. Um questionário padronizado incluiu variáveis demográficas, sociais e culturais, além da história familiar e clínica. A análise dos dados foi realizada por meio do programa SPSS para Windows e foi constituída de estatísticas descritivas e de um modelo de regressão logística condicional. Resultados: Pacientes com história de imunização (OR=16,2; IC95%=2,3–115,2), fumantes (OR=7,6; IC95%=2,1–28,2), solteiros (OR=4,7; IC95%=1,4–15,6) e que consumiam cérebro de animal (OR=3,4; IC95%=1,2–9,8) tiveram risco mais elevado de desenvolver esclerose múltipla quando comparados aos controles. Conclusão: Os resultados deste estudo podem contribuir para um melhor entendimento das características epidemiológicas dos pacientes brasileiros com esclerose múltipla.es_ES
dc.description.abstractPURPOSE. To evaluate potential risk factors for the development of multiple sclerosis in Brazilian patients. METHOD. A case control study was carried out in 81 patients enrolled at the Department of Neurology of the Hospital da Lagoa in Rio de Janeiro, and 81 paired controls. A standardized questionnaire on demographic, social and cultural variables, and medical and family history was used. Statistical analysis was performed using descriptive statistics and conditional logistic regression models with the SPSS for Windows software program. RESULTS. Having standard vaccinations (vaccinations specified by the Brazilian government) (OR=16.2; 95% CI=2.3-115.2), smoking (OR=7.6; 95% CI=2.1-28.2), being single (OR=4.7; 95% CI=1.4-15.6) and eating animal brain (OR=3.4; 95% CI=1.2-9.8) increased the risk of developing MS. CONCLUSIONS. RESULTS of this study may contribute towards better awareness of the epidemiological characteristics of Brazilian patients with multiple sclerosis.es_ES
dc.description.versionYeses
dc.identifier.citationSilva KRP da, Alvarenga RMP, Fernandez Y Fernandez O, Alvarenga H, Santos Thuler LC. Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study. Arq. Neuro-Psiquiatr. 2009 Jun;67(2A):229-34es
dc.identifier.doi10.1590/S0004-282X2009000200011
dc.identifier.essn1678-4227
dc.identifier.issn0004-282X
dc.identifier.pmid19547814
dc.identifier.urihttp://hdl.handle.net/10668/468
dc.journal.titleArquivos de Neuro-Psiquiatria
dc.language.isoen
dc.publisherAcademia Brasileira de Neurologia - ABNEUROes
dc.relation.publisherversionhttp://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-282X2009000200011&lng=es&nrm=iso&tlng=enes
dc.rights.accessRightsopen access
dc.subjectImmunizationes
dc.subjectTobaccoes
dc.subjectSingle persones
dc.subjectConsumption of animal braines
dc.subjectEsclerosis Múltiplees
dc.subjectFactores de Riesgoes
dc.subjectInmunizaciónes
dc.subjectTabacoes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studieses
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis::Multiple Sclerosis, Chronic Progressivees
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaireses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factorses
dc.subject.meshMedical Subject Headings::Geographicals::Geographic Locations::Americas::South America::Braziles
dc.subject.meshMedical Subject Headings::Check Tags::Femalees
dc.subject.meshMedical Subject Headings::Check Tags::Malees
dc.titlePotential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study.es
dc.titlePotenciais fatores de risco para o desenvolvimento de esclerose múltipla no Rio de Janeiro: um estudo caso controlees
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

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