Publication:
SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs) (2018).

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Date

2018-11-07

Authors

Gonzalez-Flores, E
Serrano, R
Sevilla, I
Viudez, A
Barriuso, J
Benavent, M
Capdevila, J
Jimenez-Fonseca, P
Lopez, C
Garcia-Carbonero, R

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Springer
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Abstract

NENs are a heterogeneous family of tumors of challenging diagnosis and clinical management. Their incidence and prevalence continue to rise across all sites, stages and grades. Although improved diagnostic techniques have led to earlier detection and stage migration, the improved prognosis documented over time for advanced gastrointestinal and pancreatic neuroendocrine tumors also reflect improvements in therapy. The aim of this guideline is to update practical recommendations for the diagnosis and treatment of gastroenteropancreatic and lung NENs. Diagnostic procedures, histological classification and therapeutic options are briefly discussed, including surgery, liver-directed therapy, peptide receptor radionuclide therapy, and systemic hormonal, cytotoxic or targeted therapy, and treatment algorithms are provided.

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MeSH Terms

Bronchial Neoplasms
Clinical Trials as Topic
Combined Modality Therapy
Disease Management
Gastrointestinal Neoplasms
Humans
Neuroendocrine Tumors
Pancreatic Neoplasms
Practice Guidelines as Topic
Prognosis
Societies, Medical

DeCS Terms

Manejo de la enfermedad
Neoplasias gastrointestinales
Neoplasias pancreáticas
Neoplasias de los bronquios
Sociedades médicas
Terapia combinada
Tumores neuroendocrinos

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Keywords

Diagnosis, Gastroenteropancreatic, Guidelines, Lung, Neuroendocrine neoplasms, Neuroendocrine tumors, Therapy

Citation

González-Flores E, Serrano R, Sevilla I, Viúdez A, Barriuso J, Benavent M, et al. SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs) (2018). Clin Transl Oncol. 2019 Jan;21(1):55-63