Publication:
Infective endocarditis in hypertrophic cardiomyopathy: A multicenter, prospective, cohort study.

dc.contributor.authorDominguez, Fernando
dc.contributor.authorRamos, Antonio
dc.contributor.authorBouza, Emilio
dc.contributor.authorMuñoz, Patricia
dc.contributor.authorValerio, Maricela C
dc.contributor.authorFariñas, M Carmen
dc.contributor.authorde Berrazueta, José Ramón
dc.contributor.authorZarauza, Jesús
dc.contributor.authorPericás Pulido, Juan Manuel
dc.contributor.authorParé, Juan Carlos
dc.contributor.authorde Alarcón, Arístides
dc.contributor.authorSousa, Dolores
dc.contributor.authorRodriguez Bailón, Isabel
dc.contributor.authorMontejo-Baranda, Miguel
dc.contributor.authorNoureddine, Mariam
dc.contributor.authorGarcía Vázquez, Elisa
dc.contributor.authorGarcia-Pavia, Pablo
dc.date.accessioned2023-01-25T08:33:54Z
dc.date.available2023-01-25T08:33:54Z
dc.date.issued2016
dc.description.abstractInfective endocarditis (IE) complicating hypertrophic cardiomyopathy (HCM) is a poorly known entity. Although current guidelines do not recommend IE antibiotic prophylaxis (IEAP) in HCM, controversy remains.This study sought to describe the clinical course of a large series of IE HCM and to compare IE in HCM patients with IE patients with and without an indication for IEAP.Data from the GAMES IE registry involving 27 Spanish hospitals were analyzed. From January 2008 to December 2013, 2000 consecutive IE patients were prospectively included in the registry. Eleven IE HCM additional cases from before 2008 were also studied. Clinical, microbiological, and echocardiographic characteristics were analyzed in IE HCM patients (n = 34) and in IE HCM reported in literature (n = 84). Patients with nondevice IE (n = 1807) were classified into 3 groups: group 1, HCM with native-valve IE (n = 26); group 2, patients with IEAP indication (n = 696); group 3, patients with no IEAP indication (n = 1085). IE episode and 1-year follow-up data were gathered.One-year mortality in IE HCM was 42% in our study and 22% in the literature. IE was more frequent, although not exclusive, in obstructive HCM (59% and 74%, respectively). Group 1 exhibited more IE predisposing factors than groups 2 and 3 (62% vs 40% vs 50%, P 
dc.identifier.doi10.1097/MD.0000000000004008
dc.identifier.essn1536-5964
dc.identifier.pmcPMC4937928
dc.identifier.pmid27368014
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937928/pdf
dc.identifier.unpaywallURLhttps://doi.org/10.1097/md.0000000000004008
dc.identifier.urihttp://hdl.handle.net/10668/10231
dc.issue.number26
dc.journal.titleMedicine
dc.journal.titleabbreviationMedicine (Baltimore)
dc.language.isoen
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationHospital Costa del Sol
dc.organizationHospital Universitario Virgen del Rocío
dc.page.numbere4008
dc.pubmedtypeComparative Study
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subject.meshAged
dc.subject.meshCardiomyopathy, Hypertrophic
dc.subject.meshCohort Studies
dc.subject.meshEndocarditis, Bacterial
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshProspective Studies
dc.titleInfective endocarditis in hypertrophic cardiomyopathy: A multicenter, prospective, cohort study.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number95
dspace.entity.typePublication

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