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Validation of a Spanish version of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis.

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2016-02-22

Authors

Muñoz, Gerard
Buxó, Maria
de Gracia, Javier
Olveira, Casilda
Martinez-Garcia, Miguel Angel
Giron, Rosa
Polverino, Eva
Alvarez, Antonio
Birring, Surinder S
Vendrell, Montserrat

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Abstract

The Leicester Cough Questionnaire (LCQ) has been validated in non-cystic fibrosis bronchiectasis (NCFBC). The present study aimed to create and validate a Spanish version of the LCQ (LCQ-Sp) in NCFBC. The LCQ-Sp was developed following a standardized protocol. For reliability, we assessed internal consistency and the change in score over a 15-day period in stable state. For responsiveness, we assessed the change in scores between visit 1 and the first exacerbation. For validity, we evaluated convergent validity through correlation with the Saint George's Respiratory Questionnaire (SGRQ) and discriminant validity. Two hundred fifty-nine patients (118 mild bronchiectasis, 90 moderate bronchiectasis and 47 severe bronchiectasis) were included. Internal consistency was high for the total scoring and good for the different domains (Cronbach's α: 0.86-0.91). The test-retest reliability shows an intraclass correlation coefficient of 0.87 for the total score. The mean LCQ-Sp score at visit 1 decreased at the beginning of an exacerbation (15.13 ± 4.06 vs. 12.24 ± 4.64; p

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Adult
Aged
Bronchiectasis
Cough
Disease Progression
Female
Humans
Longitudinal Studies
Male
Middle Aged
Patient Reported Outcome Measures
Prospective Studies
Reproducibility of Results
Severity of Illness Index
Surveys and Questionnaires
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Keywords

Bronchiectasis, cough, patient-reported outcome, quality of life, questionnaire

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