Publication: Validation of a Spanish version of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis.
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Date
2016-02-22
Authors
Muñoz, Gerard
Buxó, Maria
de Gracia, Javier
Olveira, Casilda
Martinez-Garcia, Miguel Angel
Giron, Rosa
Polverino, Eva
Alvarez, Antonio
Birring, Surinder S
Vendrell, Montserrat
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Abstract
The Leicester Cough Questionnaire (LCQ) has been validated in non-cystic fibrosis bronchiectasis (NCFBC). The present study aimed to create and validate a Spanish version of the LCQ (LCQ-Sp) in NCFBC. The LCQ-Sp was developed following a standardized protocol. For reliability, we assessed internal consistency and the change in score over a 15-day period in stable state. For responsiveness, we assessed the change in scores between visit 1 and the first exacerbation. For validity, we evaluated convergent validity through correlation with the Saint George's Respiratory Questionnaire (SGRQ) and discriminant validity. Two hundred fifty-nine patients (118 mild bronchiectasis, 90 moderate bronchiectasis and 47 severe bronchiectasis) were included. Internal consistency was high for the total scoring and good for the different domains (Cronbach's α: 0.86-0.91). The test-retest reliability shows an intraclass correlation coefficient of 0.87 for the total score. The mean LCQ-Sp score at visit 1 decreased at the beginning of an exacerbation (15.13 ± 4.06 vs. 12.24 ± 4.64; p
Description
MeSH Terms
Adult
Aged
Bronchiectasis
Cough
Disease Progression
Female
Humans
Longitudinal Studies
Male
Middle Aged
Patient Reported Outcome Measures
Prospective Studies
Reproducibility of Results
Severity of Illness Index
Surveys and Questionnaires
Translations
Aged
Bronchiectasis
Cough
Disease Progression
Female
Humans
Longitudinal Studies
Male
Middle Aged
Patient Reported Outcome Measures
Prospective Studies
Reproducibility of Results
Severity of Illness Index
Surveys and Questionnaires
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Keywords
Bronchiectasis, cough, patient-reported outcome, quality of life, questionnaire