Publication:
Targeted treatment approaches in refractory germ cell tumors.

Simple item page
dc.contributor.authorGalvez-Carvajal, Laura
dc.contributor.authorSanchez-Muñoz, Alfonso
dc.contributor.authorRibelles, Nuria
dc.contributor.authorSaez, Maribel
dc.contributor.authorBaena, Javier
dc.contributor.authorRuiz, Sofia
dc.contributor.authorIthurbisquy, Catherine
dc.contributor.authorAlba, Emilio
dc.date.accessioned2023-02-08T14:40:12Z
dc.date.available2023-02-08T14:40:12Z
dc.date.issued2019-09-25
dc.description.abstractGerm cell tumors (GCTs) are the most common type of solid tumor amongst patients between 15 and 35 years of age. They are also one of the types of tumor with the highest cure rate, due to their high sensitivity to cisplatin based chemotherapy. Nonetheless, around 15-20% of metastatic patients will not have curative options after a relapse on the first and second line. This proves that new therapeutic options for these refractory GCTs patients need to be developed. This article offers a bibliographic review of all studies using targeted treatment or immunotherapy for refractory GCTs patients.
dc.identifier.doi10.1016/j.critrevonc.2019.09.005
dc.identifier.essn1879-0461
dc.identifier.pmid31634730
dc.identifier.unpaywallURLhttps://doi.org/10.1016/j.critrevonc.2019.09.005
dc.identifier.urihttp://hdl.handle.net/10668/15022
dc.journal.titleCritical reviews in oncology/hematology
dc.journal.titleabbreviationCrit Rev Oncol Hematol
dc.language.isoen
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationHospital Universitario Regional de Málaga
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.page.number130-138
dc.pubmedtypeJournal Article
dc.pubmedtypeReview
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectGerm cell tumors
dc.subjectTargeted therapy
dc.subjectTesticular tumors
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAnimals
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols
dc.subject.meshCisplatin
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMolecular Targeted Therapy
dc.subject.meshNeoplasm Recurrence, Local
dc.subject.meshNeoplasms, Germ Cell and Embryonal
dc.subject.meshSeminoma
dc.subject.meshTeratoma
dc.subject.meshTesticular Neoplasms
dc.subject.meshYoung Adult
dc.titleTargeted treatment approaches in refractory germ cell tumors.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number143
dspace.entity.typePublication

Files

Collections

SAS - Hospital Universitario Virgen de la Victoria
Instituto de Investigación Biomédica de Málaga - Plataforma Bionand (IBIMA)
SAS - Hospital Regional Universitario de Málaga

© 2023 – Repositorio Institucional de Salud de Andalucía - Fundación Pública Andaluza Progreso y Salud - Consejería de Salud y Consumo de la Junta de Andalucía