Ex Vivo and In Vivo Stem Cells-Based Tissue Engineering Strategies for Their Use in Regenerative Medicine.

Abstract

Tissue engineering is an emergent discipline focused on the generation of bioartificial tissue-like substitutes through the combination of biomaterials, cells, and growth factors. In this context, stem cell-based strategies have made substantial contributions in the field. Researchers worldwide have demonstrated that stem cells have an extraordinary capability to differentiate into different cell lineages, promote tissue regeneration, release a wide range of growth factors, and modulate the host immune response. Based on the current impact of tissue engineering and stem cells in medicine, Stem Cells International set out to publish a special issue focused on the “Ex Vivo and In Vivo Stem Cell-Based Tissue Engineering Strategies for Their Use in Regenerative Medicine.” This special issue resulted in a collection of nine outstanding articles which include two reviews and seven original studies made by recognized researchers from seven countries across Europe, Asia, South America, and North America.