Publication:
Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia.

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Date

2022-07-16

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Sanz-Cánovas, Jaime
López-Sampalo, Almudena
Cobos-Palacios, Lidia
Ricci, Michele
Hernández-Negrín, Halbert
Mancebo-Sevilla, Juan José
Álvarez-Recio, Elena
López-Carmona, María Dolores
Pérez-Belmonte, Luis Miguel
Gómez-Huelgas, Ricardo

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Abstract

The life expectancy of the population is increasing worldwide due to improvements in the prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 diabetes mellitus (T2DM) in the elderly. Sarcopenia and frailty are also frequently present in aging. These three entities share common mechanisms such as insulin resistance, chronic inflammation, and mitochondrial dysfunction. The coexistence of these situations worsens the prognosis of elderly patients. In this paper, we review the main measures for the prevention and management of sarcopenia and/or frailty in elderly patients with T2DM.

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Aged
Aging
Diabetes Mellitus, Type 2
Frail Elderly
Frailty
Humans
Sarcopenia

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elderly, frailty, sarcopenia, type 2 diabetes mellitus

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