Publication:
Pneumocystis primary infection in non-immunosuppressed infants in Lima, Peru.

dc.contributor.authorOchoa, Theresa J
dc.contributor.authorBustamante, Beatriz
dc.contributor.authorGarcia, Coralith
dc.contributor.authorNeyra, Edgar
dc.contributor.authorMendoza, Karina
dc.contributor.authorCalderón, Enrique J
dc.contributor.authorLe Gal, Solene
dc.contributor.authorMiller, Robert F
dc.contributor.authorPonce, Carolina A
dc.contributor.authorNevez, Gilles
dc.contributor.authorVargas, Sergio L
dc.date.accessioned2023-05-03T15:10:40Z
dc.date.available2023-05-03T15:10:40Z
dc.date.issued2021-09-04
dc.description.abstractTo provide original data on Pneumocystis primary infection in non-immunosuppressed infants from Peru. A cross sectional study was performed. Infants less than seven months old, without any underlying medical conditions attending the "well baby" outpatient clinic at one hospital in Lima, Peru were prospectively enrolled during a 15-month period from November 2016 to February 2018. All had a nasopharyngeal aspirate (NPA) for detection of P. jirovecii DNA using a PCR assay, regardless of respiratory symptoms. P. jirovecii DNA detection was considered to represent pulmonary colonization contemporaneous with Pneumocystis primary infection. Associations between infants' clinical and demographic characteristics and results of P. jirovecii DNA detection were analyzed. P. jirovecii DNA was detected in 45 of 146 infants (30.8%) and detection was not associated with concurrent respiratory symptoms in 40 of 45 infants. Infants with P. jirovecii had a lower mean age when compared to infants not colonized (p Pneumocystis primary infection in this single site in Lima, Peru, was most frequently observed in 2-3-month-old infants, in winter and spring seasons, and with higher detection rates being associated with household conditions favoring close inter-individual contacts and potential transmission of P. jirovecii.
dc.identifier.doi10.1016/j.mycmed.2021.101202
dc.identifier.essn1773-0449
dc.identifier.pmid34598108
dc.identifier.unpaywallURLhttps://discovery.ucl.ac.uk/10134217/1/1-s2.0-S1156523321000925-main.pdf
dc.identifier.urihttp://hdl.handle.net/10668/22401
dc.issue.number1
dc.journal.titleJournal de mycologie medicale
dc.journal.titleabbreviationJ Mycol Med
dc.language.isoen
dc.organizationHospital Universitario Virgen del Rocío
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.page.number101202
dc.pubmedtypeJournal Article
dc.rights.accessRightsopen access
dc.subjectInfants
dc.subjectPeru
dc.subjectPneumocystis jirovecii,Pulmonary colonization
dc.subjectPrimary infection
dc.subject.meshCross-Sectional Studies
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshPeru
dc.subject.meshPneumocystis
dc.subject.meshPneumocystis carinii
dc.subject.meshPneumonia, Pneumocystis
dc.titlePneumocystis primary infection in non-immunosuppressed infants in Lima, Peru.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number32
dspace.entity.typePublication

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